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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170552-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab170552-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$237.90
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Ab170552-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$567.90
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Ab170552-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$927.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Sotigalimab (anti-CD40) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to CD40, >95%, high purity, Human IgG1, AGONIST of Tumor necrosis factor receptor superfamily member 5 agonist |
|---|---|
| Synonyms | B-cell surface antigen CD40 | Bp50 | CD40L receptor | CDw40 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD40 |
| Application | ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | AGONIST |
| Mechanism of action | AGONIST of Tumor necrosis factor receptor superfamily member 5 agonist |
| Product Description |
Sotigalimab (anti-CD40), a CD40 agonistic monoclonal antibody, can be used for the research of metastatic pancreatic adenocarcinoma. Purity: >95% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 144.54 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2305607-45-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Sotigalimab (anti-CD40) (Ab170552) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 with Sotigalimab (anti-CD40) (Ab170552) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Sotigalimab (anti-CD40) (Ab170552) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD40 (red) with Sotigalimab (anti-CD40) (Ab170552) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Sotigalimab (anti-CD40) (Ab170552) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD40 (red) with Sotigalimab (anti-CD40) (Ab170552). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Sotigalimab (anti-CD40) (Ab170552) - SEC
The purity of Sotigalimab (anti-CD40) (Ab170552) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 02, 2023 | Ab170552 | |
| Certificate of Analysis | Nov 02, 2023 | Ab170552 |
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