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SRK181 (anti-TGFb1) - Primary antibody, specific to TGFB1, Human IgG4SP

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab190128
Grouped product items
SKU Size
Availability
Price Qty
Ab190128-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab190128-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
Ab190128-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,329.90
Ab190128-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,129.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name SRK181 (anti-TGFb1) - Primary antibody, specific to TGFB1, Human IgG4SP
Synonyms Cartilage-inducing factor antibody | CED antibody | Differentiation inhibiting factor antibody | DPD1 antibody | LAP antibody | Latency-associated peptide antibody | Prepro transforming growth factor beta 1 antibody | TGF beta 1 antibody | TGF beta antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TGFB1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

SRK181 (anti-TGFb1) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. SRK181 (anti-TGF beta 1) plays an important role in cancer.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg
Protein Function
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2640981-30-0

Associated Targets(Human)

TGFB1 Tbio Transforming growth factor beta-1 proprotein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TGFB1 Tbio Transforming growth factor beta-1 (34 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

SRK181 (anti-TGFb1) (Ab190128) - ELISA
Immobilized Recombinant Human TGF-beta 1 protein (rp152261) at 1.0 μg/mL can bind SRK181 (anti-TGFb1) (Ab190128) with the EC50 of 84.57 ng/mL.

SRK181 (anti-TGFb1) (Ab190128) - SEC
The purity of SRK181 (anti-TGFb1) (Ab190128) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0910149 Certificate of Analysis Sep 05, 2024 Ab190128
ZJ24F0910148 Certificate of Analysis Sep 05, 2024 Ab190128

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