This is a demo store. No orders will be fulfilled.

Fresolimumab (anti-TGFb1) - Primary antibody, specific to TGFB1, >95%, high purity, Human IgG4SP, INHIBITOR of Transforming growth factor beta-1 inhibitor, INHIBITOR of Transforming growth factor beta-1 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab170872
Grouped product items
SKU Size
Availability
Price Qty
Ab170872-100μg
100μg
10
$129.90
Ab170872-1mg
1mg
4
$627.90
Ab170872-5mg
5mg
1
$1,767.90
Ab170872-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,817.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Fresolimumab (anti-TGFb1) - Primary antibody, specific to TGFB1, >95%, high purity, Human IgG4SP, INHIBITOR of Transforming growth factor beta-1 inhibitor
Synonyms Cartilage-inducing factor antibody | CED antibody | Differentiation inhibiting factor antibody | DPD1 antibody | LAP antibody | Latency-associated peptide antibody | Prepro transforming growth factor beta 1 antibody | TGF beta 1 antibody | TGF beta antibo
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TGFB1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Transforming growth factor beta-1 inhibitor
Product Description

Fresolimumab (anti-TGFb1) is a high-affinity fully human monoclonal antibody that neutralizes the active form of human TGFβ1, TGFβ2, and TGFβ3. Fresolimumab (anti-TGFb1) can be used for the research of cancer and fibrotic diseases.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.9 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 172.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 948564-73-6

Associated Targets(Human)

TGFB1 Tbio Transforming growth factor beta-1 proprotein (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TGFB1 Tbio Transforming growth factor beta-1 (34 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Fresolimumab (anti-TGFb1) (Ab170872) - ELISA
Immobilized Human Latent TGF-beta 1/TGFB1-his at 2.0 μg/mL can bind Fresolimumab (anti-TGFb1) (Ab170872) with the EC₅₀ of 60.47 ng/mL.

Fresolimumab (anti-TGFb1) (Ab170872) - SEC
The purity of Fresolimumab (anti-TGFb1) (Ab170872) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303726 Certificate of Analysis Mar 26, 2024 Ab170872
ZJ24F0303725 Certificate of Analysis Mar 26, 2024 Ab170872
ZJ24F0303724 Certificate of Analysis Mar 26, 2024 Ab170872

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.