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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170872-100μg
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100μg |
10
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$129.90
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Ab170872-1mg
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1mg |
4
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$627.90
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Ab170872-5mg
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5mg |
1
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$1,767.90
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Ab170872-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,817.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Fresolimumab (anti-TGFb1) - Primary antibody, specific to TGFB1, >95%, high purity, Human IgG4SP, INHIBITOR of Transforming growth factor beta-1 inhibitor |
|---|---|
| Synonyms | Cartilage-inducing factor antibody | CED antibody | Differentiation inhibiting factor antibody | DPD1 antibody | LAP antibody | Latency-associated peptide antibody | Prepro transforming growth factor beta 1 antibody | TGF beta 1 antibody | TGF beta antibo |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TGFB1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Transforming growth factor beta-1 inhibitor |
| Product Description |
Fresolimumab (anti-TGFb1) is a high-affinity fully human monoclonal antibody that neutralizes the active form of human TGFβ1, TGFβ2, and TGFβ3. Fresolimumab (anti-TGFb1) can be used for the research of cancer and fibrotic diseases. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 172.1 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 948564-73-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Fresolimumab (anti-TGFb1) (Ab170872) - ELISA
Immobilized Human Latent TGF-beta 1/TGFB1-his at 2.0 μg/mL can bind Fresolimumab (anti-TGFb1) (Ab170872) with the EC₅₀ of 60.47 ng/mL.
Fresolimumab (anti-TGFb1) (Ab170872) - SEC
The purity of Fresolimumab (anti-TGFb1) (Ab170872) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 26, 2024 | Ab170872 | |
| Certificate of Analysis | Mar 26, 2024 | Ab170872 | |
| Certificate of Analysis | Mar 26, 2024 | Ab170872 |
Starting at $109.90
Starting at $89.90