Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab175656-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$69.90
|
|
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Ab175656-1mg
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1mg |
5
|
$339.90
|
|
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Ab175656-5mg
|
5mg |
1
|
$869.90
|
|
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Ab175656-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,379.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Sirukumab (anti-IL-6) - Primary antibody, specific to IL6, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-6 inhibitor |
|---|---|
| Synonyms | Interleukin BSF 2 antibody | B cell differentiation factor antibody | B cell stimulatory factor 2 antibody | B-cell stimulatory factor 2 antibody | BSF 2 antibody | BSF-2 antibody | BSF2 antibody | CDF antibody | CTL differentiation factor antibody | Cyto |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL6 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-6 inhibitor |
| Product Description |
Sirukumab (anti-IL-6) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab (anti-IL-6) has the potential for active lupus nephritis research. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 144.58 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1194585-53-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Sirukumab (anti-IL-6) (Ab175656) - ELISA
Immobilized hu-IL-6 at 1.0 μg/mL can bind Sirukumab (anti-IL-6) (Ab175656) with the EC₅₀ of 45.55 ng/mL.
Sirukumab (anti-IL-6) (Ab175656) - SEC
The purity of Sirukumab (anti-IL-6) (Ab175656) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 28, 2023 | Ab175656 | |
| Certificate of Analysis | Dec 28, 2023 | Ab175656 |
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