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Sirukumab (anti-IL-6) - Primary antibody, specific to IL6, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-6 inhibitor, INHIBITOR of Interleukin-6 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175656
Grouped product items
SKU Size
Availability
Price Qty
Ab175656-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab175656-1mg
1mg
5
$339.90
Ab175656-5mg
5mg
1
$869.90
Ab175656-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,379.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Sirukumab (anti-IL-6) - Primary antibody, specific to IL6, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-6 inhibitor
Synonyms Interleukin BSF 2 antibody | B cell differentiation factor antibody | B cell stimulatory factor 2 antibody | B-cell stimulatory factor 2 antibody | BSF 2 antibody | BSF-2 antibody | BSF2 antibody | CDF antibody | CTL differentiation factor antibody | Cyto
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL6
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Interleukin-6 inhibitor
Product Description

Sirukumab (anti-IL-6) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab (anti-IL-6) has the potential for active lupus nephritis research.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.58 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1194585-53-9

Associated Targets(Human)

IL6 Tclin Interleukin-6 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Sirukumab (anti-IL-6) (Ab175656) - ELISA
Immobilized hu-IL-6 at 1.0 μg/mL can bind Sirukumab (anti-IL-6) (Ab175656) with the EC₅₀ of 45.55 ng/mL.

Sirukumab (anti-IL-6) (Ab175656) - SEC
The purity of Sirukumab (anti-IL-6) (Ab175656) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202212 Certificate of Analysis Dec 28, 2023 Ab175656
ZJ23F1202211 Certificate of Analysis Dec 28, 2023 Ab175656

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