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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209767-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$109.90
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Ab209767-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
|
|
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Ab209767-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209767-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Chugai SK2 (anti-IL-6) - Primary antibody, specific to IL6, Human IgG1 |
|---|---|
| Synonyms | Interleukin BSF 2 antibody | B cell differentiation factor antibody | B cell stimulatory factor 2 antibody | B-cell stimulatory factor 2 antibody | BSF 2 antibody | BSF-2 antibody | BSF2 antibody | CDF antibody | CTL differentiation factor antibody | Cyto |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induc |
| Host species | Human |
| Specificity | IL6 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Chugai SK2 (anti-IL-6) is a humanized mouse monoclonal antibody that specifically binds to IL-6 and strongly inhibits IL-6 functions. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.46 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Chugai SK2 (anti-IL-6) (Ab209767) - ELISA
Immobilized Recombinant Human IL-6 protein (rp186549) at 1.0 μg/mL can bind Chugai SK2 (anti-IL-6) (Ab209767) with the EC₅₀ of 107.4 ng/mL.
Chugai SK2 (anti-IL-6) (Ab209767) - ELISA
Immobilized Recombinant Nhis-IL-6 protein at 2.0 μg/mL can bind Chugai SK2 (anti-IL-6) (Ab209767) with the EC50 of 20.53 ng/mL.
Chugai SK2 (anti-IL-6) (Ab209767) - SEC
The purity of Chugai SK2 (anti-IL-6) (Ab209767) is more than 95% verified by HPLC.
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