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PharmPure™ GMP Portfolio
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Recombinant Mouse IL-4 ProteinSpecies: Mouse Accession #: P07750Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.Synonyms: B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4...
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Recombinant Human GDNF GMP ProteinSpecies: Human Accession #: P39905-1Expression system: HEK293 Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 2-12 ng/mL in the presence of Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera. The specific activity of recombinant human GDNF is >5.0 x 10^5 units/mg, which is calibrated against the human GDNF Reference Standard (NIBSC code: 09/266). Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human GFRα‑1/GDNF Rα‑1 Fc Chimera at 1 µg/mL can bind Recombinant Human GDNF with an apparent Kd <1 nM.Synonyms: Glial Cell line-derived Growth Factor | Astrocyte-derived trophic factor | ATF | ATF1 | ATF2 | GDNF | glial cell deri...
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Recombinant Human HGF GMP ProteinSpecies: Human Accession #: P14210-1Expression system: HEK293 Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is equal or less than 4.00 ng/mL. The specific activity of recombinant human HGF is >1.0 x 10^6 IU/mg, which is calibrated against the human HGF WHO International Standard (NIBSC code: 96/564).Synonyms: Hepatocyte Growth Factor | deafness, autosomal recessive 39 | DFNB39 | EC 3.4.21 | EC 3.4.21.7 | fibroblast-derived t...
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Recombinant Human Wnt-3a GMP ProteinSpecies: Human Accession #: NP_149122.1Expression system: HEK293 Protein Tag: C-hFc Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to induce Topflash reporterBioactivity in CHO-K1 cells. The ED50 for this effect is ＜30ng/ml.Synonyms: MGC119418 | MGC119419 | MGC119420 | protein Wnt-3a | wingless-type MMTV integration site family, member 3A | Wnt3a | ...
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Recombinant Human Noggin GMP ProteinSpecies: Human Accession #: Q13253.1Expression system: HEK293 Protein Tag: C-hFc Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.1-0.4 μg/mL in the presence of 30 ng/mL of Recombinant Human BMP‑4Synonyms: NOG | Noggin | SYM1 | symphalangism 1 (proximal) | synostoses (multiple) syndrome 1 | SYNS1 | SYNS1A
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Recombinant Human Fetuin B ProteinSpecies: Human Accession #: Q9UGM5Expression system: HEK293 Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC (RLU). The IC50 value is ≤100nM.Synonyms: FETUB | Fetuin B | fetuin beta | fetuin phosphoprotein | fetuin-B | Fetuin-like protein | 16G2 | Gugu | IRL685
