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Osemitamab (anti-CLDN18.2) - Primary antibody, specific to CLDN18, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab183000
Grouped product items
SKU Size
Availability
Price Qty
Ab183000-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab183000-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
Ab183000-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,089.90
Ab183000-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,749.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Osemitamab (anti-CLDN18.2) - Primary antibody, specific to CLDN18, Human IgG1
Synonyms Claudin-18 antibody | CLD18_HUMAN antibody | CLDN18 antibody | SFTA5 antibody | SFTPJ antibody | SFTA5 | SFTPJ | TST001 | Claudin 18 antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Host species Human
Specificity CLDN18
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Osemitamab (anti-CLDN18.2) is an IgG1 antibody targeting to human claudin-18.2. Osemitamab (anti-CLDN18.2) consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab (anti-CLDN18.2) in combination with Capecitabine and Oxaliplatin, can be used for G/GEJ cancer study.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 146.48 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2460539-61-9

Associated Targets(Human)

CLDN18 Tbio Claudin-18 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Osemitamab (anti-CLDN18.2) (Ab183000) - SEC
The purity of Osemitamab (anti-CLDN18.2) (Ab183000) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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