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MSI2 Mouse mAb - Primary antibody, specific to MSI2, Mouse IgG1

    Application:
  • ELISA
  • IHC
  • WB
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: 2C11
  • Conjugation: Unconjugated
In stock
Item Number
Ab116122
Grouped product items
SKU Size
Availability
Price Qty
Ab116122-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab116122-50μl
50μl
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$207.90
Ab116122-100μl
100μl
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$327.90
Ab116122-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,967.90

mAb(2C11); Mouse anti Human MSI2 Antibody; WB, IHC, ELISA; Unconjugated

Basic Description

Product Name MSI2 Mouse mAb - Primary antibody, specific to MSI2, Mouse IgG1
Synonyms FLJ36569 antibody | MGC3245 antibody | Msi2 antibody | MSI2/HOXA9 fusion gene, included antibody | MSI2H antibody | MSI2H_HUMAN antibody | Musashi 2 antibody | Musashi homolog 2 antibody | Musashi RNA binding protein 2 antibody | Musashi, Drosophila, homo
Specifications & Purity ExactAb™, Validated, Carrier Free, 1.0mg/mL
Host species Mouse
Specificity MSI2
Immunogen Purified recombinant fragment of human MSI2(AA: 1-190) expressed in E. Coli.
Positive Control WB: HeLa, Hep G2 and A549 cell. IHC: Ovarian cancer tissues, Cerebellum tissues.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human MSI2 Antibody, Monoclonal antibody, could be used for WB, IHC, ELISA and so on.

Application:
WB: 1/500 - 1/2000. Predicted molecular weight: 35 kDa.
IHC: 1/200-1/1000
ELISA: 1/10000


Protein Function:
Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

Post-translational:
Phosphorylated.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration 1.0mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Associated Targets(Human)

MSI2 Tbio RNA-binding protein Musashi homolog 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

MSI2 Mouse mAb (Ab116122) - Western Blot
All lanes: MSI2 Mouse mAb (Ab116122) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 35 kDa
Observed band size: 35, 37 kDa
Exposure time: 126.8 s


MSI2 Mouse mAb (Ab116122) - Western Blot
All lanes: MSI2 Mouse mAb (Ab116122) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/20000 dilution

Predicted band size: 35 kDa
Observed band size: 35, 39 kDa
Exposure time: 37.0 s

MSI2 Mouse mAb (Ab116122) - IHC
Immunohistochemical analysis of paraffin-embedded ovarian cancer using MSI2 Mouse mAb (Ab116122) with DAB staining.

MSI2 Mouse mAb (Ab116122) - IHC
Immunohistochemical analysis of cerebellum tissues using MSI2 Mouse mAb (Ab116122) with DAB staining.

Application

Application Dilution info
ELISA

1/10000

IHC

1/200-1/1000

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0800773 Certificate of Analysis Aug 08, 2023 Ab116122
ZJ23F0800774 Certificate of Analysis Aug 08, 2023 Ab116122

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