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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183435-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$89.90
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Ab183435-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$449.90
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Ab183435-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,069.90
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Ab183435-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,719.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Vesencumab (anti-NRP1) - Primary antibody, specific to NRP1, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of Neuropilin-1 inhibitor |
|---|---|
| Synonyms | A5 protein antibody | BDCA4 antibody | BLOOD DENDRITIC CELL ANTIGEN 4 antibody | CD304 antibody | Neuropilin-1 antibody | Neuropilin1 antibody | NP1 antibody | NPN1 antibody | NRP 1 antibody | NRP antibody | NRP1 antibody | NRP1_HUMAN antibody | transmemb |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | NRP1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Neuropilin-1 inhibitor |
| Product Description |
Vesencumab (anti-NRP1) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab (anti-NRP1) binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab (anti-NRP1) has anti-angiogenic and anti-neoplastic activities. Vesencumab (anti-NRP1) can be used in the research of metastatic solid tumors, including ovarian cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.22 kDa |
| Purification Method | Protein A purified |
| Purity | >95% (SDS-PAGE&SEC) |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1205533-60-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Vesencumab (anti-NRP1) (Ab183435) - ELISA
Immobilized Recombinant Human NRP1-His protein at 2.0 μg/mL can bind Vesencumab (anti-NRP1) (Ab183435) with the EC₅₀ of 3.345 ng/mL.
Vesencumab (anti-NRP1) (Ab183435) - SEC
The purity of Vesencumab (anti-NRP1) (Ab183435) is more than 95% verified by HPLC.