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Vesencumab (anti-NRP1) - Primary antibody, specific to NRP1, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of Neuropilin-1 inhibitor, INHIBITOR of Neuropilin-1 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab183435
Grouped product items
SKU Size
Availability
Price Qty
Ab183435-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab183435-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$449.90
Ab183435-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,069.90
Ab183435-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,719.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Vesencumab (anti-NRP1) - Primary antibody, specific to NRP1, >95% (SDS-PAGE&SEC), high purity, Human IgG1, INHIBITOR of Neuropilin-1 inhibitor
Synonyms A5 protein antibody | BDCA4 antibody | BLOOD DENDRITIC CELL ANTIGEN 4 antibody | CD304 antibody | Neuropilin-1 antibody | Neuropilin1 antibody | NP1 antibody | NPN1 antibody | NRP 1 antibody | NRP antibody | NRP1 antibody | NRP1_HUMAN antibody | transmemb
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity NRP1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Neuropilin-1 inhibitor
Product Description

Vesencumab (anti-NRP1) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab (anti-NRP1) binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab (anti-NRP1) has anti-angiogenic and anti-neoplastic activities. Vesencumab (anti-NRP1) can be used in the research of metastatic solid tumors, including ovarian cancer.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.22 kDa
Purification Method Protein A purified
Purity >95% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1205533-60-3

Associated Targets(Human)

NRP1 Tchem Neuropilin-1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Vesencumab (anti-NRP1) (Ab183435) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling NRP1 (red) with Vesencumab (anti-NRP1) (Ab183435). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Vesencumab (anti-NRP1) (Ab183435) - ELISA
Immobilized Recombinant Human NRP1-His protein at 2.0 μg/mL can bind Vesencumab (anti-NRP1) (Ab183435) with the EC₅₀ of 3.345 ng/mL.

Vesencumab (anti-NRP1) (Ab183435) - SEC
The purity of Vesencumab (anti-NRP1) (Ab183435) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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