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Edrecolomab (anti-EpCAM) - Primary antibody, specific to EPCAM, Human IgG2, CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent, CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent

    Application:
  • ELISA
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2a
  • Conjugation: Unconjugated
In stock
Item Number
Ab175518
Grouped product items
SKU Size
Availability
Price Qty
Ab175518-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab175518-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90
Ab175518-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
Ab175518-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$959.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Mouse IgG2a; CHO; ELISA, Flow Cytometry; Unconjugated

Basic Description

Product Name Edrecolomab (anti-EpCAM) - Primary antibody, specific to EPCAM, Human IgG2, CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent
Synonyms 17 1A antibody | 323/A3 antibody | Adenocarcinoma associated antigen antibody | Adenocarcinoma-associated antigen antibody | Antigen identified by monoclonal antibody AUA1 antibody | AUA1 antibody | CD326 antibody | CD326 antigen antibody | Cell surface g
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Pla
Host species Mouse
Specificity EPCAM
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type CROSS-LINKING AGENT
Mechanism of action CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent
Product Description

Edrecolomab (anti-EpCAM) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab (anti-EpCAM) shows anti-tumor activity and can be used in colorectal carcinoma research.

Product Properties

Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 12 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS 156586-89-9

Associated Targets(Human)

EPCAM Tbio Epithelial cell adhesion molecule (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Edrecolomab (anti-EpCAM) (Ab175518) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling EpCAM (red) with Edrecolomab (anti-EpCAM) (Ab175518) at 1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Edrecolomab (anti-EpCAM) (Ab175518) - ELISA
Immobilized Recombinant Human EPCAM protein (rp170132) at 1.0 μg/mL can bind Edrecolomab (anti-EpCAM) (Ab175518) with the EC50 of 0.74 μg/mL.

Edrecolomab (anti-EpCAM) (Ab175518) - SEC
The purity of Edrecolomab (anti-EpCAM) (Ab175518) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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