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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175518-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab175518-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$269.90
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Ab175518-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$599.90
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Ab175518-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$959.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Mouse IgG2a; CHO; ELISA, Flow Cytometry; Unconjugated
| Product Name | Edrecolomab (anti-EpCAM) - Primary antibody, specific to EPCAM, Human IgG2, CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent |
|---|---|
| Synonyms | 17 1A antibody | 323/A3 antibody | Adenocarcinoma associated antigen antibody | Adenocarcinoma-associated antigen antibody | Antigen identified by monoclonal antibody AUA1 antibody | AUA1 antibody | CD326 antibody | CD326 antigen antibody | Cell surface g |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Pla |
| Host species | Mouse |
| Specificity | EPCAM |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | CROSS-LINKING AGENT |
| Mechanism of action | CROSS-LINKING AGENT of Epithelial cell adhesion molecule cross-linking agent |
| Product Description |
Edrecolomab (anti-EpCAM) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A, expressed on epithelial tissues and on various carcinomas. Edrecolomab (anti-EpCAM) shows anti-tumor activity and can be used in colorectal carcinoma research.
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| Isotype | Human IgG2 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 12 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 156586-89-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Edrecolomab (anti-EpCAM) (Ab175518) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling EpCAM (red) with Edrecolomab (anti-EpCAM) (Ab175518) at 1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
Edrecolomab (anti-EpCAM) (Ab175518) - ELISA
Immobilized Recombinant Human EPCAM protein (rp170132) at 1.0 μg/mL can bind Edrecolomab (anti-EpCAM) (Ab175518) with the EC50 of 0.74 μg/mL.
Edrecolomab (anti-EpCAM) (Ab175518) - SEC
The purity of Edrecolomab (anti-EpCAM) (Ab175518) is more than 95% verified by HPLC.
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