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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209902-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209902-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$509.90
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Ab209902-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209902-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Citatuzumab (anti-EpCAM) - Primary antibody, specific to EPCAM, Human IgG1 |
|---|---|
| Synonyms | 17 1A antibody | 323/A3 antibody | Adenocarcinoma associated antigen antibody | Adenocarcinoma-associated antigen antibody | Antigen identified by monoclonal antibody AUA1 antibody | AUA1 antibody | CD326 antibody | CD326 antigen antibody | Cell surface g |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Pla |
| Host species | Human |
| Specificity | EPCAM |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Citatuzumab (anti-EpCAM) is a recombinant immunotoxin that composed of humanized monoclonal antibody targeting EpCAM. It has antitumor activity and can be used in treatment of cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.4 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 896731-82-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Citatuzumab (anti-EpCAM) (Ab209902) - Flow Cytometry
Flow Cytometry analysis of MCF7 cells labelling EpCAM (red) with Citatuzumab (anti-EpCAM) (Ab209902) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Citatuzumab (anti-EpCAM) (Ab209902) - ELISA
Immobilized Recombinant Human EpCAM protein (rp170132) at 1.0 μg/mL can bind Citatuzumab (anti-EpCAM) (Ab209902) with the EC50 of 21.84 ng/mL.
Citatuzumab (anti-EpCAM) (Ab209902) - SEC
The purity of Citatuzumab (anti-EpCAM) (Ab209902) is more than 95% verified by HPLC.
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