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Antibody-drug Conjugates(ADC)

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  1. Trastuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  ERBB2
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 180288-69-1
    Formula:  C6470H10012N1726O2013S42        Molecular Weight: 145531.50
    IUPAC Name:  2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES:  C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI:  InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
    Synonyms: 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
  2. Cetuximab (anti-EGFR), Antibody of epidermal growth factor receptor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  EGFR
      Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 205923-56-4
    Formula:         Molecular Weight: 145543.35
    Synonyms: C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference...
  3. Gemtuzumab (anti-CD33), BINDING AGENT of Myeloid cell surface antigen CD33 binding agent
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD33
      Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
      Species reactivity(Reacts with): Human    Isotype: Human IgG4SP    
      Host species: Human    Conjugation: Unconjugated    
    Cas Number: 220578-59-6
    Synonyms: CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33...
  4. Brentuximab vedotin (anti-CD30), Antibody of CD30
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNFRSF8
      Short Overview: Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: MC-VC-PAB-MMAE    
    Cas Number: 914088-09-8
    SMILES:  [Brentuximab vedotin]
    Synonyms: CD 30 antibody | CD30 antibody | CD30 antigen antibody | CD30L receptor antibody | Cytokine receptor CD30 antibody | ...
  5. Enfortumab vedotin-ejfv (anti-Nectin-4), Antibody of nectin cell adhesion molecule 4
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  NECTIN4
      Short Overview: Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: MC-VC-PAB-MMAE    
    Cas Number: 1346452-25-2
    SMILES:  [Enfortumab vedotin-ejfv]
    Synonyms: DKFZp686K05193 antibody | EDSS1 antibody | Ig superfamily receptor LNIR antibody | Nectin 4 antibody | Nectin-4 antib...
  6. Glembatumumab vedotin (anti-GPNMB), BINDING AGENT of Transmembrane glycoprotein NMB binding agent
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  GPNMB
      Short Overview: Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)    
      Species reactivity(Reacts with): Human, Mouse    Isotype: Human IgG2SA    
      Host species: Human    Conjugation: MC-VC-PAB-MMAE    
    Cas Number: 1182215-65-1
    Synonyms: Glycoprotein (transmembrane) nmb antibody | Glycoprotein nmb antibody | Glycoprotein nmb like protein antibody | Gpnm...
  7. Polatuzumab vedotin-piiq (anti-CD79b), Antibody of CD79B
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  CD79B
      Short Overview: Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: MC-VC-PAB-MMAE    
    Cas Number: 1313206-42-6
    SMILES:  [Polatuzumab vedotin]
    Synonyms: AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein...
  8. Tisotumab vedotin (anti-Tissue Factor), Antibody of coagulation factor III; tissue factor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  F3
      Short Overview: Purity≥90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)    
      Species reactivity(Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
      Host species: Human    Conjugation: MC-VC-PAB-MMAE    
    Cas Number: 1418731-10-8
    Synonyms: CD142 antibody | CD142 antigen antibody | Coagulation factor III (thromboplastin tissue factor) antibody | Coagulatio...
  9. Trastuzumab emtansine (anti-ERBB2), INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  ERBB2
      Short Overview: Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (SMCC-DM1)    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: SMCC-DM1    
    Cas Number: 1018448-65-1        Compound CID:  163341910
    SMILES:  C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)show more
    Synonyms: Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
  10. Belantamab mafodotin (anti-BCMA), Antibody of B cell maturation antigen
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNFRSF17
      Short Overview: Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAF)    
      Species reactivity(Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: MC-VC-PAB-MMAF    
    Cas Number: 2050232-20-5
    SMILES:  [Belantamab mafodotin]
    Synonyms: B cell maturation antigen antibody | B cell maturation factor antibody | B cell maturation protein antibody | B-cell ...
  11. Depatuxizumab mafodotin (anti-EGFR), BINDING AGENT of Epidermal growth factor receptor erbB1 binding agent
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  EGFR
      Short Overview: Purity>95% ( SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (Mc-MMAF)    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: Mc-MMAF    
    Cas Number: 1585973-65-4
    Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
  12. Lorvotuzumab mertansine (anti-NCAM1), BINDING AGENT of Neural cell adhesion molecule 1 binding agent
      Application: 
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  NCAM1
      Short Overview: Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (SMCC-DM1)    
      Species reactivity(Reacts with): Human    Isotype: Human IgG1    
      Host species: Human    Conjugation: SMCC-DM1    
    Cas Number: 1008106-64-6
    Synonyms: antigen MSK39 identified by monoclonal antibody 5.1H11 antibody | antigen recognized by monoclonal antibody 5.1H11 an...
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