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tumor_necrosis_factors
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Recombinant Mouse TNF-alpha ProteinSpecies: Mouse Accession #: P06804Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.01 EU/μgBioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.Synonyms: Recombinant Murine Tumor Necrosis Factor alpha (rMuTNF-α) | APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, mo...
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Recombinant Human TRAIL ProteinSpecies: Human Accession #: P50591Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to induce apoptosis in Jurkat cells (Human T Lymphocyte Cells). The ED₅₀ for this effect is typically <12ng/mL.Synonyms: Apo-2 ligand | Apo-2L | Protein TRAIL | TNF-related apoptosis-inducing ligand
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Recombinant Human TNF-alpha ProteinSpecies: Human Accession #: P01375Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.Synonyms: APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
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Recombinant Human RANK ProteinSpecies: Human Accession #: Q9Y6Q6Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0 × 104 IU/mg in the presence of 15 ng/ml of recombinant sRANK Ligand.Synonyms: CD 265 | CD265 | FEO | LOH18CR1 | Loss of heterozygosity 18 chromosomal region 1 | mRANK | ODFR | OFE | OPTB7 | Osteo...
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Recombinant Rat TNF-alpha ProteinSpecies: Rat Accession #: P16599Expression system: HEK293 Protein Tag: C-His Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The EC50 for this effect is typically <5 pg/mL.Synonyms: APC1 protein | Cachectin | Cachetin | RATTNF | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alph...
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Recombinant Human BAFFR/TNFRSF13C ProteinSpecies: Human Accession #: Q96RJ3Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 μg/ml in the presence of 1.0 μg/ml of rHuBAFF.Synonyms: BAFF R | BAFFR | BR3 | CD268 | TNFRSF13C | CVID4 | BAFF-R | BROMIX | prolixin
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Recombinant Human TNFRSF1A ProteinSpecies: Human Accession #: P19438Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <0.1 EU/μgBioactivity: Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the TNF-alpha mediated cytotoxicity in the L-929 cells is less than 0.05 μg/ml in the presence of 0.25 ng/mL of rHuTNF-alpha.Synonyms: CD120a antigen | CD120a | FPF | p55 | p55-R | p60 | TNF RI | TNFARMGC19588 | TNF-R | TNF-R1 | TNFR1TBP1 | TNFR55 | TN...
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Recombinant Human Osteoprotegerin ProteinSpecies: Human Accession #: O00300Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Fully biologically active when compared to standard. The ED50 as determined by neutralizing the stimulation of U937 cells is less than 10 ng/ml in the presence of 10 ng/mL soluble rHuRANKL (sRANKL).Synonyms: OCIF | OCIFMGC29565 | OPG | OPGtumor necrosis factor receptor superfamily member 11B | Osteoclastogenesis inhibitory ...
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Recombinant Human HVEM/TNFRSF14 ProteinSpecies: Human Accession #: Q92956Expression system: Pichia pastoris Protein Tag: C-hFc Endotoxin Concentration: <0.1 EU/μgBioactivity: Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.Synonyms: ATAR | CD270 antigen | CD270 | CD40-like protein | Herpes virus entry mediator A | Herpesvirus entry mediator A | Hve...
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Recombinant Human CD40 Ligand/TNFSF5 ProteinSpecies: Human Accession #: P29965Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.Synonyms: CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM...
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Recombinant Human TRAIL R2/TNFRSF10B ProteinSpecies: Human Accession #: O14763Expression system: E. coli Protein Tag: No tag Endotoxin Concentration: <1.0 EU/μgBioactivity: Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed.Synonyms: CD262 antigen | CD262 | death domain containing receptor for TRAIL/Apo-2L | Death receptor 5 | DR5 | DR5TRICK2B | Fas...
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Recombinant Human CD30-L ProteinSpecies: Human Accession #: P32971Expression system: HEK293 Protein Tag: N-His Endotoxin Concentration: <0.1 EU/μgBioactivity: Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. The ED50 for this effect is 8-48 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody.Synonyms: CD153 antigen; CD153; CD30 antigen ligand; CD30 Ligand; CD30L; CD30-L; CD30LCD30 ligand; CD30LGMGC138144; TNFSF8; tum...
