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Inolimomab (anti-IL2RA) - Primary antibody, specific to IL2RA, Human IgG1, ANTAGONIST of Interleukin-2 receptor alpha chain antagonist, ANTAGONIST of Interleukin-2 receptor alpha chain antagonist

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab183060
Grouped product items
SKU Size
Availability
 Price Qty
Ab183060-100μg
100μg
10
$59.90
Ab183060-1mg
1mg
4
$289.90
Ab183060-5mg
5mg
1
$749.90
Ab183060-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: IL2RA
Accession#:P01589 (8) CD25 (12) Gene ID:3559 (9) IL-2 Receptor Alpha (8) IL-2R alpha (2) IL2RA (14)

Basic Description

Product Name Inolimomab (anti-IL2RA) - Primary antibody, specific to IL2RA, Human IgG1, ANTAGONIST of Interleukin-2 receptor alpha chain antagonist
Synonyms CD25 antibody | IDDM10 antibody | IL 2 RA antibody | IL 2 receptor subunit alpha antibody | IL 2R alpha chain antibody | IL 2R subunit alpha antibody | IL-2 receptor subunit alpha antibody | IL-2-RA antibody | IL-2R subunit alpha antibody | IL2 RA antibod
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL2RA
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action ANTAGONIST of Interleukin-2 receptor alpha chain antagonist
Product Description

Inolimomab (anti-IL2RA) is an anti-interleukin-2 receptor (IL-2R) α chain monoclonal antibody. Inolimomab (anti-IL2RA) improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD).
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 145.34 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 152981-31-2

Associated Targets(Human)

IL2RA Tclin Interleukin-2 receptor subunit alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IL2RA Tclin Interleukin-2 receptor alpha chain (2 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Inolimomab (anti-IL2RA) (Ab183060) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling IL2RA (red) with Inolimomab (anti-IL2RA) (Ab183060) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Inolimomab (anti-IL2RA) (Ab183060) - ELISA
Immobilized Recombinant Human CD25/IL-2R alpha Protein (rp169618) at 1.0 μg/mL can bind Inolimomab (anti-IL2RA) (Ab183060) with the EC ₅₀ of 4.70 ng/mL.

Inolimomab (anti-IL2RA) (Ab183060) - SEC
The purity of Inolimomab (anti-IL2RA) (Ab183060) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0606998 Certificate of Analysis Jun 19, 2024 Ab183060
ZJ24F0606997 Certificate of Analysis Jun 19, 2024 Ab183060
ZJ24F0606996 Certificate of Analysis Jun 19, 2024 Ab183060

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