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GRP78 BiP Mouse mAb - Primary antibody, specific to GRP78 BiP, Mouse IgG2b

    Application:
  • Animal Model
  • Blocking
  • Flow Cytometry
  • Functional Assay
  • WB
  • Host species: Mouse
  • Reactive species: Human,Mouse
  • Isotype: Mouse IgG2b
  • Clone Number: C38
  • Conjugation: Unconjugated
In stock
Item Number
Ab106528
Grouped product items
SKU Size
Availability
Price Qty
Ab106528-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab106528-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab106528-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab106528-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90

mAb (C38); Mouse anti Human/Mouse GRP78 BiP Antibody; in vivo GRP78 blockade, in vitro GRP78 blockade, WB, Flow; Unconjugated

Basic Description

Product Name GRP78 BiP Mouse mAb - Primary antibody, specific to GRP78 BiP, Mouse IgG2b
Synonyms HEL-S-89n | Bip | Sez7 | mBiP | Grp78 | SEZ-7 | Hsce70 | baffled | D2Wsu17e | D2Wsu141e | 78 kDa glucose-regulated protein | BIP | Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 | FLJ26106 | GRP78 | GRP-78 | GRP78BIP | Heat shock 70 kDa protei
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Mouse
Specificity GRP78 BiP
Immunogen Recombinant protein of murine GRP78 (AA 1-655)
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human/Mouse GRP78 BiP Antibody, Monoclonal (C38), could be used for in vivo GRP78 blockade, in vitro GRP78 blockade, WB, Flow and so on.

Application:

in vivo GRP78 blockade: Use at an assay dependent concentration. 

in vitro GRP78 blockade: Use at an assay dependent concentration. 

WB: Use at an assay dependent concentration.

Flow: Use at an assay dependent concentration.
Protein Function
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Product Properties

Isotype Mouse IgG2b
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

HSPA5 Tchem Endoplasmic reticulum chaperone BiP (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

GRP78 BiP Mouse mAb (Ab106528) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling GRP78 BiP (red) with GRP78 BiP Mouse mAb (Ab106528) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
WB

Use at an assay dependent concentration.

Flow Cytometry

Use at an assay dependent concentration.

in vivo GRP78 blockade

Use at an assay dependent concentration

in vitro GRP78 blockade

Use at an assay dependent concentration

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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