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GRB2 Mouse mAb - Primary antibody, specific to GRB2, Mouse IgG1

COA COA
    Application:
  • WB
  • Host species: Mouse
  • Reactive species: Human,Mouse,Rat
  • Isotype: Mouse IgG1
  • Clone Number: 5G3-E7-F11
  • Conjugation: Unconjugated
In stock
Item Number
Ab106387
Grouped product items
SKU Size
Availability
 Price Qty
Ab106387-10μl
10μl
5
$66.90
Ab106387-50μl
50μl
2
$199.90
Ab106387-100μl
100μl
1
$299.90
Ab106387-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (5G3-E7-F11); Mouse anti Human GRB2 Antibody; WB; Unconjugated

View related series
Click to view target information: GRB2
Accession#:P62993 (2) Gene ID:2885 (2) GRB2 (2)

Basic Description

Product Name GRB2 Mouse mAb - Primary antibody, specific to GRB2, Mouse IgG1
Synonyms GRB2 | ASH | Growth factor receptor-bound protein 2 | Adapter protein GRB2 | Protein Ash | SH2/SH3 adapter GRB2 | Abundant SRC homology antibody | Adapter protein GRB2 antibody | ASH antibody | Ash protein antibody | EGFRBP GRB2 antibody | Epidermal growt
Specifications & Purity ExactAb™, Validated, 4.2 mg/mL
Host species Mouse
Specificity GRB2
Immunogen Recombinant protein of human GRB2 (AA 1-217).
Positive Control WB：K562, Raji, Jurkat, Ramos, C6, NIH/3T3, HeLa, MCF7 and A431 cell lysates.
Conjugation Unconjugated
Grade ExactAb™, Validated
Product Description

Mouse anti Human GRB2 Antibody, Monoclonal (5G3-E7-F11), could be used for WB and so on .
Application:
WB: 1/500-1/1000
Protein Function
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

Product Properties

Isotype Mouse IgG1
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration 4.2 mg/mL
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

GRB2 Tchem Growth factor receptor-bound protein 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

GRB2 Mouse mAb (Ab106387) - Western Blot
All lanes: GRB2 Mouse mAb (Ab106387) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040)at 1/20000 dilution

Predicted band size: 25 kDa
Observed band size: 25 kDa
Exposure time: 7.2 s

Application

Application Dilution info
WB

1/500-1/1000

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0901054 Certificate of Analysis Sep 14, 2023 Ab106387
ZJ23F0901055 Certificate of Analysis Sep 14, 2023 Ab106387

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