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GITR/CD357 Rat mAb - Primary antibody, specific to GITR/CD357, Rat IgG2b

COA COA
    Application:
  • Animal Model
  • Flow Cytometry
  • Functional Assay
  • Stimulation
  • Host species: Rat
  • Reactive species: Mouse
  • Isotype: Rat IgG2b
  • Clone Number: DTA-1
  • Conjugation: Unconjugated
In stock
Item Number
Ab105420
Grouped product items
SKU Size
Availability
 Price Qty
Ab105420-10μg
10μg
9
$29.90
Ab105420-50μg
50μg
4
$69.90
Ab105420-100μg
100μg
2
$109.90
Ab105420-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody; Flow, in vivo GITR stimulation; Unconjugated

View related series
Click to view target information: TNFRSF18
Accession#: O35714 (6) CD357 (2) Flow Cytometry (1158) Gene ID: 21936 (7) GITR (7)

Basic Description

Product Name GITR/CD357 Rat mAb - Primary antibody, specific to GITR/CD357, Rat IgG2b
Synonyms Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related pr
Specifications & Purity Carrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Rat
Specificity GITR/CD357
Immunogen Mouse CD25+ CD4+ T cells
Conjugation Unconjugated
Grade Azide Free, Carrier Free, Validated
Product Description

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow, in vivo GITR stimulation and so on.
Application:
Flow: Use at an assay dependent concentration.
in vivo GITR stimulation: Use at an assay dependent concentration.
Protein Function
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Properties

Isotype Rat IgG2b
Light Chain Type lambda
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

GITR/CD357 Rat mAb (Ab105420) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling GITR/CD357 with GITR/CD357 Rat mAb (Ab105420) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).

GITR/CD357 Rat mAb (Ab105420) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling GITR/CD357 (red) with GITR/CD357 Rat mAb (Ab105420) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

Use at an assay dependent concentration.
in vivo GITR stimulation

Use at an assay dependent concentration.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0708261 Certificate of Analysis Jul 15, 2024 Ab105420
ZJ24F0708260 Certificate of Analysis Jul 15, 2024 Ab105420
ZJ24F0708259 Certificate of Analysis Jul 15, 2024 Ab105420

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