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GITR/CD357 Rat mAb (AF647) - Primary antibody, specific to GITR/CD357, Rat IgG2b

COA COA
    Application:
  • Flow Cytometry
  • Host species: Rat
  • Reactive species: Mouse
  • Isotype: Rat IgG2b
  • Clone Number: DTA-1
  • Conjugation: AF647
In stock
Item Number
Ab190295
Grouped product items
SKU Size
Availability
 Price Qty
Ab190295-10μg
10μg
4
$89.90
Ab190295-25μg
25μg
3
$169.90
Ab190295-100μg
100μg
1
$419.90
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Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (AF647); Flow

View related series
Click to view target information: TNFRSF18
Accession#: O35714 (6) AF647 (119) AITR (6) Flow Cytometry (1158) Gene ID: 21936 (7) GITR (7)

Basic Description

Product Name GITR/CD357 Rat mAb (AF647) - Primary antibody, specific to GITR/CD357, Rat IgG2b
Synonyms Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein |
Specifications & Purity ExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL
Biochemical and Physiological Mechanisms Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Host species Rat
Specificity GITR/CD357
Immunogen Mouse CD25+ CD4+ T cells
Positive Control Flow: C57BL/6 mouse splenocytes.
Conjugation AF647
Excitation(nm) Red Laser(633nm)
Emission(nm) 668nm
Ex/Em(nm) Ex:650nm;Em:668nm
Grade Em:668nm, Ex:650nm, ExactAb™, Validated
Product Description

Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow.

Product Properties

Isotype Rat IgG2b
Light Chain Type lambda
Purification Method Protein G purified
Concentration 0.5 mg/mL
Storage Temp Store at 2-8°C,Protected from light,Do not freeze
Shipped In Wet ice
Stability And Storage The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Associated Targets(Human)

TNFRSF18 Tbio Tumor necrosis factor receptor superfamily member 18 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

GITR/CD357 Rat mAb (AF647) (Ab190295) - Flow Cytometry
Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (PE) (Ab179011) and either Rat IgG (AF647) (Ab190071; Left panel) or GITR/CD357 Rat mAb (AF647) (Ab190295; Right panel) at 1 μg/mL. Total viable cells were used for analysis.

Application

Application Dilution info
Flow Cytometry

≤0.3μg/test

For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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