Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab190293-10μg
|
10μg |
3
|
$69.90
|
|
|
Ab190293-25μg
|
25μg |
2
|
$129.90
|
|
|
Ab190293-100μg
|
100μg |
1
|
$309.90
|
|
mAb (DTA-1); Rat anti Mouse GITR/CD357 Antibody (APC); Flow
| Product Name | GITR/CD357 Rat mAb (APC) - Primary antibody, specific to GITR/CD357, Rat IgG2b |
|---|---|
| Synonyms | Gitr | Activation-inducible TNFR family receptor | AITR | AITRTNF receptor superfamily activation-inducible protein | CD357 antigen | CD357 | GITR-D | GITRtumor necrosis factor receptor superfamily member 18 | Glucocorticoid-induced TNFR-related protein | |
| Specifications & Purity | ExactAb™, Validated, Ex:650nm, Em:660nm, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Host species | Rat |
| Specificity | GITR/CD357 |
| Immunogen | Mouse CD25+ CD4+ T cells |
| Positive Control | Flow: C57BL/6 mouse splenocytes. |
| Conjugation | APC |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 660nm |
| Ex/Em(nm) | Ex:650nm;Em:660nm |
| Grade | Em:660nm, Ex:650nm, ExactAb™, Validated |
| Product Description |
Rat anti Mouse GITR/CD357 Antibody, Monoclonal (DTA-1), could be used for Flow. |
| Isotype | Rat IgG2b |
|---|---|
| Light Chain Type | lambda |
| Purification Method | Protein G purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Do not freeze |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
GITR/CD357 Rat mAb (APC) (Ab190293) - Flow Cytometry
Two-color flow cytometric analysis of GITR/CD357 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD25 Rat mAb (PE) (Ab179011) and either Rat IgG Isotype Control Antibody (APC) (Ab180313; Left panel) or GITR/CD357 Rat mAb (APC) (Ab190293; Right panel) at 1 μg/mL. Total viable cells were used for analysis.
| Application | Dilution info |
|---|---|
| Flow Cytometry |
≤0.3 μg/test,
the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume
|
Starting at $36.90
Starting at $89.90
Starting at $39.90
Starting at $29.90