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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170540-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$89.90
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Ab170540-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$417.90
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Ab170540-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$1,047.90
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Ab170540-10mg
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10mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$1,707.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Farletuzumab (anti-FOLR1) - Primary antibody, specific to FOLR1, >95%, high purity, Human IgG1, INHIBITOR of Folate receptor alpha inhibitor |
|---|---|
| Synonyms | Adult folate-binding protein | FBP | Folate receptor 1 | Folate receptor, adult | FR-alpha | KB cells FBP | Ovarian tumor-associated antigen MOv18 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | FOLR1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Folate receptor alpha inhibitor |
| Product Description |
Farletuzumab is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer. Purity |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 52.2 kDa (Heavy Chain), under reducing conditions; 181.9 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 896723-44-7 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Farletuzumab (anti-FOLR1) (Ab170540) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling FOLR1 (red) with Farletuzumab (anti-FOLR1) (Ab170540). Goat Anti-Human IgG (FITC) (Ab175834) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Farletuzumab (anti-FOLR1) (Ab170540) - SEC
The purity of Farletuzumab (anti-FOLR1) (Ab170540) is more than 95% verified by HPLC.
Farletuzumab (anti-FOLR1) (Ab170540) - ELISA
Immobilized huFOLR1 at 2 μg/mL can bind Farletuzumab (anti-FOLR1) (Ab170540) with the EC₅₀ of 18.95 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Aug 25, 2023 | Ab170540 | |
| Certificate of Analysis | Aug 25, 2023 | Ab170540 | |
| Certificate of Analysis | Aug 25, 2023 | Ab170540 |