This is a demo store. No orders will be fulfilled.

Dupilumab (anti-IL-4Ra) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL-4R, >95%, high purity, Human IgG4SP, Antibody of Interleukin-4 receptor subunit α, Antibody of Interleukin-4 receptor subunit α

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab169296
Grouped product items
SKU Size
Availability
Price Qty
Ab169296-100μg
100μg
10
$59.90
Ab169296-1mg
1mg
4
$267.90
Ab169296-5mg
5mg
1
$837.90
Ab169296-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,317.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Dupilumab (anti-IL-4Ra) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL-4R, >95%, high purity, Human IgG4SP, Antibody of Interleukin-4 receptor subunit α
Synonyms CD124 antibody | IL 4R alpha antibody | IL-4 receptor subunit alpha antibody | IL-4-binding protein antibody | IL-4R subunit alpha antibody | IL-4R-alpha antibody | IL-4RA antibody | IL4-BP antibody | Il4r antibody | IL4R nirs variant 1 antibody | IL4RA a
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL-4R
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of Interleukin-4 receptor subunit α
Product Description

Dupilumab is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.4 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 187.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1190264-60-8

Associated Targets(Human)

IL4R Tclin Interleukin-4 receptor subunit alpha (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
IL4R Tclin Interleukin-4 receptor subunit alpha (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Dupilumab (anti-IL-4Ra) (Ab169296) - Flow Cytometry
HEK293 human embryonic kidney cell line transfected with rhuIL-4R-full length was stained with Dupilumab (anti-IL-4Ra) (Ab169296).

Dupilumab (anti-IL-4Ra) (Ab169296) - SEC
The purity of Dupilumab (anti-IL-4Ra) (Ab169296) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303678 Certificate of Analysis Mar 25, 2024 Ab169296
ZJ24F0303677 Certificate of Analysis Mar 25, 2024 Ab169296
ZJ24F0303676 Certificate of Analysis Mar 25, 2024 Ab169296

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.