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CD11b Mouse mAb - Primary antibody, specific to CD11b, Mouse IgG1

COA COA
    Application:
  • Flow Cytometry
  • IHC
  • IP
  • WB
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: ICRF44
  • Conjugation: Unconjugated
In stock
Item Number
Ab093725
Grouped product items
SKU Size
Availability
 Price Qty
Ab093725-10μg
10μg
10
$19.90
Ab093725-50μg
50μg
4
$39.90
Ab093725-100μg
100μg
2
$49.90
Ab093725-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$369.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (ICRF44); Mouse anti Human CD11b Antibody; Flow, WB, IHC, IP; Unconjugated

View related series
Click to view target information: ITGAM
Accession#:P11215 (21) CD11 (6) CD11b (11) Flow Cytometry (1158) Gene ID:3684 (21) ITGAM (5)

Basic Description

Product Name CD11b Mouse mAb - Primary antibody, specific to CD11b, Mouse IgG1
Synonyms CD11B | antigen CD11b (p170) | CD11 antigen-like family member B | CD11b antigen | CD11b | Cell surface glycoprotein MAC-1 subunit alpha | Complement component 3 receptor 3 subunit | CR-3 alpha chain | CR3A | CR3AMGC117044 | Integrin alpha M | integrin al
Specifications & Purity Carrier Free, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&HPLC), See COA
Host species Mouse
Specificity CD11b
Immunogen Rheumatoid synovial cells and human monocytes.
Conjugation Unconjugated
Grade Azide Free, Carrier Free, Low Endotoxin, Validated
Product Description

Mouse anti Human CD11b Antibody, Monoclonal (ICRF44), could be used for Flow, WB, IHC, IP and so on.
Application
Flow: ≤ 1.0µg/100w cells  
WB: Use at an assay dependent concentration.
IP: Use at an assay dependent concentration.
IHC: Use at an assay dependent concentration.
Protein Function
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

ITGAM Tbio Integrin alpha-M (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD11b Mouse mAb (Ab093725) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD11b with CD11b Mouse mAb (Ab093725) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Biotin) (Ab180306) (left panel) and detected with SA-PE (rp156150). 

CD11b Mouse mAb (Ab093725) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD11b (red) with CD11b Mouse mAb (Ab093725) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Mouse IgG Isotype Control Antibody (Biotin) (Ab180306). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
WB

Use at an assay dependent concentration.
IP

Use at an assay dependent concentration.
IHC

Use at an assay dependent concentration.
Flow Cytometry

≤ 1.0µg/100w cells  

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0707917 Certificate of Analysis Jul 08, 2024 Ab093725
ZJ24F0707916 Certificate of Analysis Jul 08, 2024 Ab093725
ZJ24F0707915 Certificate of Analysis Jul 08, 2024 Ab093725

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