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Hematologica Malignancies CAR Targets

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  1. Recombinant Human IL-3R alpha/CD123 Protein
      Species: Human    Accession #: P26951-1    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized recombinant Human IL3 at 4 μg/mL (100 μL/well) can bind recombinant Human IL3RA, the EC50 of Human IL3RA is 5.3 μg/mL.    
    Synonyms: CD123 antigen | CD123 | hIL3Ra | hIL-3Ra | IL-3 R alpha | IL-3 receptor subunit alpha | IL3R alpha | IL-3R alpha | IL...
  2. Recombinant Human CD33 Protein
      Species: Human    Accession #: P20138    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: 1、Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. The ED50 for this effect is 1‑4 µg/mL. 2、Immobilized Recombinant Human CD33 Protein (rp143966) at 2.0 μg/mL can bind Gemtuzumab (anti-CD33) (Ab175859). The ED50 for this effect is 391.3 ng/mL.    
    Synonyms: CD33 antigen (gp67) | CD33 antigen | CD33 molecule | CD33 | FLJ00391 | gp67 | myeloid cell surface antigen CD33 | p67...
  3. Recombinant Human CD22 Protein
      Species: Human    Accession #: P20273    
      Expression system: HEK293    Protein Tag: C-Fc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Recombinant Human CD22 Protein (rp143882) at 1 μg/mL can bind Recombinant CD22 Antibody (Ab094265) with a EC50 is 4.6 ng/mL.    
    Synonyms: B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic...
  4. Recombinant Human CD99 Protein
      Species: Human    Accession #: P14209-1    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized CD99 Mouse mAb (Ab006798) at 2.0 μg/mL can bind biotinylated Recombinant Human CD99 Protein (rp144165) , the EC50 for this effect is 13.15 ng/mL.    
    Synonyms: 120000000 | Antigen identified by monoclonal 12E7, Y homolog | Antigen identified by monoclonal antibodies 12E7, F21 ...
  5. Recombinant Human CD38 Protein
      Species: Human    Accession #: P28907    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Human CD38 Protein at 1μg/mL (100 μL/well) can bind CD38 Rabbit pAb with a linear range of 0.244-3.2 ng/mL.    
    Synonyms: 2'-phospho-ADP-ribosyl cyclase | 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.2...
  6. Recombinant Human CD72 Protein
      Species: Human    Accession #: P21854    
      Expression system: HEK293    Protein Tag: C-hFc & His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Measured by the ability of the immobilized protein to induce IFN-gamma secretion in NK‑92 human natural killer lymphoma cells. The ED50 for this effect is 3-15 μg/mL.    
    Synonyms: B cell differentiation antigen CD72; B-cell differentiation antigen CD72; CD_antigen=CD72; CD72; CD72 antigen; CD72 m...
  7. Recombinant Human CD5 Protein
      Species: Human    Accession #: P06127    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Recombinant Human CD5 can bind CD5 Antibody with a linear range of 0.800‑8.00 ng/mL.    
    Synonyms: CD 5 | CD5 | CD5 antigen | CD5 antigen (p56 62) | CD5 molecule | CD5_HUMAN | LEU1 | LyA | Lymphocyte antigen T1/Leu-1...
  8. Recombinant Human CD4 Protein
      Species: Human    Accession #: P01730    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Measured by the ability of the immobilized protein to support the adhesion of HeLa human cervical epithelial carcinoma cells. The ED50 for this effect is 40.0 ng/mL. Measured by its binding ability in a functional ELISA. Immobilized Human CD4 protein (rp175911) at 1.0 μg/mL can bind Ibalizumab (anti-CD4) (Ab170728) with the EC50 of 52.66 ng/mL.    
    Synonyms: CD 4 | CD4 | CD4 (L3T4) | CD4 antigen | CD4 antigen (p55) | CD4 molecule | CD4 receptor | CD4+ Lymphocyte deficiency,...
  9. Recombinant Human ROR1 Protein
      Species: Human    Accession #: Q01973    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Immobilized Recombinant Human ROR1 Protein (rp176297) at 2.0 μg/mL can bind Zilovertamab (anti-ROR1) (Ab170644) , the EC50 is 16.07 ng/mL.    
    Synonyms: dJ537F10.1 | Inactive tyrosine protein kinase transmembrane receptor ROR1 | MGC99659 | Neurotrophic tyrosine kinase |...
  10. Recombinant Mouse PD-L1/B7-H1 Protein
      Species: Mouse    Accession #: Q9EP73    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <0.1 EU/μg    
      Bioactivity: Immobilized Recombinant Mouse PD-L1/B7-H1 Protein (rp154493) at 10 μg/mL can bind Recombinant Mouse PD-1 Protein (rp149974), the EC₅₀ of this effect is 3.07 μg/mL.    
    Synonyms: Programmed Death Ligand 1 | Avelumab | B7-H | B7H1 | B7-H1 | CD274 antigen | MGC142294 | CD274 molecule | CD274 | PDC...
  11. Recombinant Feline CD4 Protein
      Species: Feline    Accession #: P79355    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
    Synonyms: CD_antigen: CD4 | CD4 antigen (p55) | CD4 antigen | CD4 molecule | CD4 receptor | CD4 | CD4mut | T-cell surface antig...
  12. Recombinant Canine CD4 Protein
      Species: Canine    Accession #: P33705    
      Expression system: HEK293    Protein Tag: C-His    Endotoxin Concentration: <1.0 EU/μg    
      Bioactivity: Bioassay data are not available.    
    Synonyms: CD_antigen: CD4 | CD4 antigen (p55) | CD4 antigen | CD4 molecule | CD4 receptor | CD4 | CD4mut | T-cell surface antig...
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