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c-Met/HGFR

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    Decanoic acid
    Cas Number: 334-48-5        EC Number: 206-376-4
    Formula:  C10H20O2        Molecular Weight: 172.26
    IUPAC Name:  decanoic acid
    SMILES:  CCCCCCCCCC(=O)O
    InChIKey: GHVNFZFCNZKVNT-UHFFFAOYSA-N
    InChI:  InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
    Synonyms: Capric acid
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  2. , Agonist of GPR84
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    Decanoic acid, Agonist of GPR84
    Cas Number: 334-48-5        EC Number: 206-376-4
    Formula:  C10H20O2        Molecular Weight: 172.26
    IUPAC Name:  decanoic acid
    SMILES:  CCCCCCCCCC(=O)O
    InChIKey: GHVNFZFCNZKVNT-UHFFFAOYSA-N
    InChI:  InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
    Synonyms: Capric acid | C10:0 | NSC 5025 | CAPRIC ACID | Caprynic acid | aliphatic carboxylic acid | chemical code 128955 sodiu...
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  3. , Agonist of GPR84
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    Decanoic acid, Agonist of GPR84
    Cas Number: 334-48-5        EC Number: 206-376-4
    Formula:  C10H20O2        Molecular Weight: 172.26
    IUPAC Name:  decanoic acid
    SMILES:  CCCCCCCCCC(=O)O
    InChIKey: GHVNFZFCNZKVNT-UHFFFAOYSA-N
    InChI:  InChI=1S/C10H20O2/c1-2-3-4-5-6-7-8-9-10(11)12/h2-9H2,1H3,(H,11,12)
    Synonyms: Decanoic acid|CAPRIC ACID|334-48-5|n-Decanoic acid|n-Capric acid|Decoic acid|Decylic acid|Caprinic acid|n-Decylic aci...
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  4. , Hepatocyte growth factor receptor inhibitor
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    EMD 1214063, Hepatocyte growth factor receptor inhibitor
    Cas Number: 1100598-32-0
    Formula:  C29H28N6O2        Molecular Weight: 492.57
    IUPAC Name:  3-[1-[[3-[5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl]phenyl]methyl]-6-oxopyridazin-3-yl]benzonitrile
    SMILES:  CN1CCC(CC1)COC2=CN=C(N=C2)C3=CC=CC(=C3)CN4C(=O)C=CC(=N4)C5=CC=CC(=C5)C#N
    InChIKey: AHYMHWXQRWRBKT-UHFFFAOYSA-N
    InChI:  InChI=1S/C29H28N6O2/c1-34-12-10-21(11-13-34)20-37-26-17-31-29(32-18-26)25-7-3-5-23(15-25)19-35-28(36)9-8-27(33-35)24-6-2-4-22(14-24)16-30/h2-9,14-15,1show more
    Synonyms: Tepotinib | MSC2156119 | Benzonitrile, 3-[1,6-dihydro-1-[[3-[5-[(1-methyl-4-piperidinyl)methoxy]-2-pyrimidinyl]phenyl...
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    Ensartinib (X-396) dihydrochloride
      Grade & Purity: 
    • ≥98%
    Cas Number: 2137030-98-7        Compound CID:  138320013
    Formula:  C26H29Cl4FN6O3        Molecular Weight: 634.36
    IUPAC Name:  6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(3R,5S)-3,5-dimethylpiperazine-1-carbonyl]phenyl]pyridazine-3-carboxamide;dihydrochloride
    SMILES:  CC1CN(CC(N1)C)C(=O)C2=CC=C(C=C2)NC(=O)C3=NN=C(C(=C3)OC(C)C4=C(C=CC(=C4Cl)F)Cl)N.Cl.Cl
    InChIKey: IERUINQRGJAECT-ISUJJMBGSA-N
    InChI:  InChI=1S/C26H27Cl2FN6O3.2ClH/c1-13-11-35(12-14(2)31-13)26(37)16-4-6-17(7-5-16)32-25(36)20-10-21(24(30)34-33-20)38-15(3)22-18(27)8-9-19(29)23(22)28;;/hshow more
    Synonyms: Ensartinib hydrochloride | Ensartinib hydrochloride (USAN) | 3-Pyridazinecarboxamide, 6-amino-5-((1R)-1-(2,6-dichloro...
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    Ensartinib (X-396) dihydrochloride
      Grade & Purity: 
    • 10mM in DMSO
    Cas Number: 2137030-98-7        Compound CID:  138320013
    Formula:  C26H29Cl4FN6O3        Molecular Weight: 634.36
    IUPAC Name:  6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(3R,5S)-3,5-dimethylpiperazine-1-carbonyl]phenyl]pyridazine-3-carboxamide;dihydrochloride
    SMILES:  CC1CN(CC(N1)C)C(=O)C2=CC=C(C=C2)NC(=O)C3=NN=C(C(=C3)OC(C)C4=C(C=CC(=C4Cl)F)Cl)N.Cl.Cl
    InChIKey: IERUINQRGJAECT-ISUJJMBGSA-N
    InChI:  InChI=1S/C26H27Cl2FN6O3.2ClH/c1-13-11-35(12-14(2)31-13)26(37)16-4-6-17(7-5-16)32-25(36)20-10-21(24(30)34-33-20)38-15(3)22-18(27)8-9-19(29)23(22)28;;/hshow more
    Synonyms: Ensartinib hydrochloride|2137030-98-7|Ensartinib dihydrochloride|X-396 hydrochloride|ENSARTINIB 2HCL|X-396 dihydrochl...
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  7. , Inhibitor of MET proto-oncogene; receptor tyrosine kinase
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    Glumetinib (SCC244), Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    Cas Number: 1642581-63-2
    Formula:  C21H17N9O2S        Molecular Weight: 459.48
    IUPAC Name:  6-(1-methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonylpyrazolo[4,3-b]pyridine
    SMILES:  CN1C=C(C=N1)C2=CN3C(=NC=C3S(=O)(=O)N4C5=C(C=N4)N=CC(=C5)C6=CN(N=C6)C)C=C2
    InChIKey: RYBLECYFLJXEJX-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H17N9O2S/c1-27-11-16(7-24-27)14-3-4-20-23-10-21(29(20)13-14)33(31,32)30-19-5-15(6-22-18(19)9-26-30)17-8-25-28(2)12-17/h3-13H,1-2H3
    Synonyms: UNII-7JTT036WGX | SCC244 | SC-C244 | AC-32584 | HY-116000 | SCC244; SC-C244; SCC 244 | 6-(1-Methyl-1H-pyrazol-4-yl)-1...
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  8. , Inhibitor of MET proto-oncogene; receptor tyrosine kinase
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    Glumetinib (SCC244), Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    Cas Number: 1642581-63-2
    Formula:  C21H17N9O2S        Molecular Weight: 459.48
    IUPAC Name:  6-(1-methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]sulfonylpyrazolo[4,3-b]pyridine
    SMILES:  CN1C=C(C=N1)C2=CN3C(=NC=C3S(=O)(=O)N4C5=C(C=N4)N=CC(=C5)C6=CN(N=C6)C)C=C2
    InChIKey: RYBLECYFLJXEJX-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H17N9O2S/c1-27-11-16(7-24-27)14-3-4-20-23-10-21(29(20)13-14)33(31,32)30-19-5-15(6-22-18(19)9-26-30)17-8-25-28(2)12-17/h3-13H,1-2H3
    Synonyms: UNII-7JTT036WGX | SCC244 | SC-C244 | AC-32584 | HY-116000 | SCC244; SC-C244; SCC 244 | 6-(1-Methyl-1H-pyrazol-4-yl)-1...
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  9. , Inhibitor of MET proto-oncogene; receptor tyrosine kinase
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    JNJ-38877618(OMO-1), Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    Cas Number: 943540-74-7
    Formula:  C20H12F2N6        Molecular Weight: 374.35
    IUPAC Name:  6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline
    SMILES:  C1=CC2=C(C=CC(=C2)C(C3=NN=C4N3N=C(C=C4)C5=CC=NC=C5)(F)F)N=C1
    InChIKey: KOAWAWHSMVKCON-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H
    Synonyms: JNJ-38877618|943540-74-7|JNJ38877618|OMO-1|OMO1|6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)meth...
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  10. , Inhibitor of MET proto-oncogene; receptor tyrosine kinase
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    JNJ-38877618(OMO-1), Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    Cas Number: 943540-74-7
    Formula:  C20H12F2N6        Molecular Weight: 374.35
    IUPAC Name:  6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline
    SMILES:  C1=CC2=C(C=CC(=C2)C(C3=NN=C4N3N=C(C=C4)C5=CC=NC=C5)(F)F)N=C1
    InChIKey: KOAWAWHSMVKCON-UHFFFAOYSA-N
    InChI:  InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H
    Synonyms: GTPL10507 | 6-{difluoro[6-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline | HY-111050 | 6-(diflu...
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  11. , Hepatocyte growth factor receptor inhibitor
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    LY2801653, Hepatocyte growth factor receptor inhibitor
    Cas Number: 1206799-15-6
    Formula:  C30H22F2N6O3        Molecular Weight: 552.53
    IUPAC Name:  N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide
    SMILES:  CC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)F
    InChIKey: QHADVLVFMKEIIP-UHFFFAOYSA-N
    InChI:  InChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-1show more
    Synonyms: Merestinib|1206799-15-6|LY2801653|LY-2801653|N-(3-fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)...
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  12. Wish List Compare
    MET kinase-IN-2
      Grade & Purity: 
    • ≥98%
    Cas Number: 2101241-90-9
    Formula:  C33H27FN4O4        Molecular Weight: 562.59
    Synonyms: 1,6-Naphthyridin-4(1H)-one, 5-[[3-fluoro-4-[[7-(2-hydroxy-2-methylpropoxy)-4-quinolinyl]oxy]phenyl]amino]-3-phenyl-
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Molecule Type
  1. Small molecule 77 items
  2. Unknown 6 items
  3. Antibody 5 items
  4. Antibody drug conjugate 1 item
Target
  1. MET 54 items
  2. AXL 14 items
  3. KDR 13 items
  4. MST1R 11 items
  5. MERTK 11 items
  6. TEK 8 items
  7. FLT3 7 items
  8. NTRK2 7 items
  9. EGFR 6 items
  10. NQO2 6 items
  11. NTRK1 6 items
  12. GPR84 5 items
  13. ERBB2 5 items
  14. DDR1 4 items
  15. TYRO3 4 items
  16. BCR 4 items
  17. FLT1 4 items
  18. ABL1 4 items
  19. ALK 4 items
  20. KIT 4 items
  21. NTRK3 4 items
  22. ERBB4 3 items
  23. EPHB6 3 items
  24. RET 3 items
  25. ROS1 3 items
  26. FLT4 3 items
  27. SLK 3 items
  28. PDGFRB 3 items
  29. TIE1 3 items
  30. JAK2 3 items
  31. CSF1R 2 items
  32. SRC 2 items
  33. HMOX2 2 items
  34. HGF 2 items
  35. FGFR1 2 items
  36. PTK2B 2 items
  37. EIF5B 2 items
  38. SMO 2 items
  39. PDGFRA 2 items
  40. LTK 2 items
  41. ABL2 2 items
  42. OPA1 2 items
  43. CYP3A4 1 item
  44. CDK7 1 item
  45. EPHA2 1 item
  46. EPHA4 1 item
  47. EPHA8 1 item
  48. EPHB1 1 item
  49. EPHB4 1 item
  50. EPHA5 1 item
  51. DDR2 1 item
  52. EPHA1 1 item
  53. EPHA3 1 item
  54. PTK6 1 item
  55. SRMS 1 item
  56. STK10 1 item
  57. FRK 1 item
  58. EPHA6 1 item
  59. EPHA7 1 item
  60. EPHB2 1 item
  61. HIPK4 1 item
  62. FGFR2 1 item
  63. FGFR3 1 item
  64. PRKACG 1 item
  65. TNK1 1 item
  66. PLK4 1 item
  67. PIP4K2C 1 item
  68. RIPK2 1 item
  69. MKNK2 1 item
  70. MAP2K2 1 item
  71. MAP3K13 1 item
  72. MAP3K19 1 item
  73. LCK 1 item
  74. MAP3K12 1 item
  75. MAP4K5 1 item
  76. LYN 1 item
  77. BLK 1 item
  78. AURKC 1 item
  79. HCK 1 item
  80. MAP2K1 1 item
  81. MAP2K5 1 item
  82. MUSK 1 item
Antibody Type
  1. Primary antibody 6 items
Application
  1. Animal Model 6 items
  2. ELISA 6 items
  3. Flow Cytometry 6 items
  4. Functional Assay 6 items
Species reactivity（Reacts with)
  1. Human 6 items
  2. Cynomolgus monkey 4 items
  3. Mouse 2 items
  4. Rat 1 item
Host species
  1. Human 6 items
Clonality
  1. Recombinant 6 items
Conjugation
  1. Unconjugated 5 items
  2. MC-VC-PAB-MMAE 1 item
Isotype
  1. Human IgG1 4 items
  2. Human IgG2SA 1 item
  3. Human IgG4SP 1 item
Physical Form
  1. Liquid 6 items
  2. Solid 4 items
Purity
  1. ≥98% 47 items
  2. ≥99% 18 items
  3. ≥97% 6 items
  4. ≥95%(SDS-PAGE&SEC-HPLC) 5 items
  5. ≥96% 2 items
  6. ≥98%(HPLC) 2 items
  7. ≥90%(SDS-PAGE&SEC-HPLC) 1 item
  8. ≥95% 1 item
  9. ≥99%(GC) 1 item
  10. ≥99.5%(GC) 1 item
Source
  1. CHO supernatant 5 items
Grade
  1. Moligand™ 52 items
  2. Animal Free 6 items
  3. Azide Free 6 items
  4. Carrier Free 6 items
  5. ExactAb™ 6 items
  6. Low Endotoxin 6 items
  7. Recombinant 6 items
  8. Validated 6 items
  9. analytical standard 1 item
  10. AR 1 item
  11. CP 1 item
  12. Standard for GC 1 item
Action Type
  1. INHIBITOR 57 items
  2. AGONIST 3 items
  3. ACTIVATOR 1 item
  4. ANTAGONIST 1 item
Price
  1. $0.00 - $500.00 109 items
  2. $500.00 - $1,000.00 7 items
  3. $1,000.00 - $1,500.00 4 items
  4. $2,000.00 - $2,500.00 1 item
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