This is a demo store. No orders will be fulfilled.
c-Met/HGFR
-
JNJ-38877605, Hepatocyte growth factor receptor inhibitorCas Number: 943540-75-8Formula: C19H13F2N7 Molecular Weight: 377.35IUPAC Name: 6-[difluoro-[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinolineSMILES: CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2InChIKey: JRWCBEOAFGHNNU-UHFFFAOYSA-NInChI: InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3Synonyms: SB16606 | CCG-264826 | 6-[difluoro-[6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline | ...
-
Tivantinib (ARQ 197), Hepatocyte growth factor receptor inhibitorCas Number: 905854-02-6 Compound CID: 11494412Formula: C23H19N3O2 Molecular Weight: 369.42IUPAC Name: (3R,4R)-3-(1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraen-3-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dioneSMILES: C1CC2=C3C(=CC=C2)C(=CN3C1)C4C(C(=O)NC4=O)C5=CNC6=CC=CC=C65InChIKey: UCEQXRCJXIVODC-PMACEKPBSA-NInChI: show more
Synonyms: (+/-)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione | (+/-)-trans-3-... -
SYN1143Cas Number: 913376-84-8Formula: C31H29FN4O5 Molecular Weight: 556.59IUPAC Name: N-[3-fluoro-4-(7-methoxyquinolin-4-yl)oxyphenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxamideSMILES: CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=CC(=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC)FInChIKey: UYMSIPINLJNNOU-UHFFFAOYSA-NInChI: show more Synonyms: BDBM24465 | N-(3-Fluoro-4-((7-methoxyquinolin-4-yl)oxy)phenyl)-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2...
-
-
2,6-Dimethyl-4-(3-methyl-1H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrile(BAY-474)Cas Number: 1033767-86-0 Compound CID: 24959105Formula: C17H15N5 Molecular Weight: 289.33IUPAC Name: 2,6-dimethyl-4-(3-methyl-2H-indazol-5-yl)-1,4-dihydropyridine-3,5-dicarbonitrileSMILES: CC1=C2C=C(C=CC2=NN1)C3C(=C(NC(=C3C#N)C)C)C#NInChIKey: QKVFMAAIXZONRN-UHFFFAOYSA-NInChI: InChI=1S/C17H15N5/c1-9-14(7-18)17(15(8-19)10(2)20-9)12-4-5-16-13(6-12)11(3)21-22-16/h4-6,17,20H,1-3H3,(H,21,22)Synonyms: 3,5-Pyridinedicarbonitrile,1,4-dihydro-2,6-dimethyl-4-(3-methyl-1H-indazol-5-yl)-
-
5-Chloro-3-(thiophen-2-ylmethylene)indolin-2-oneCas Number: 186611-58-5Formula: C13H8ClNOS Molecular Weight: 261.73IUPAC Name: (3Z)-5-chloro-3-(thiophen-2-ylmethylidene)-1H-indol-2-oneSMILES: C1=CSC(=C1)C=C2C3=C(C=CC(=C3)Cl)NC2=OInChIKey: ZYHHCVFJHNWKDY-XFFZJAGNSA-NInChI: InChI=1S/C13H8ClNOS/c14-8-3-4-12-10(6-8)11(13(16)15-12)7-9-2-1-5-17-9/h1-7H,(H,15,16)/b11-7-Synonyms: 5-Chloro-3-(thiophen-2-ylmethylene)indolin-2-one
-
AMG 337, Inhibitor of CYP3A4;Inhibitor of MET proto-oncogene; receptor tyrosine kinaseCas Number: 1173699-31-4Formula: C23H22FN7O3 Molecular Weight: 463.46IUPAC Name: 6-[(1R)-1-[8-fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-oneSMILES: CC(C1=NN=C2N1C=C(C=C2F)C3=CN(N=C3)C)N4C=CC5=C(C4=O)C=C(C=N5)OCCOCInChIKey: DWHXUGDWKAIASB-CQSZACIVSA-NInChI: show more Synonyms: AMG-337|1173699-31-4|AMG 337|08WG8S0L8D|AMG 337 [WHO-DD]|(r)-6-(1-(8-fluoro-6-(1-methyl-1h-pyrazol-4-yl)-[1,2,4]triaz...
-
AMG 337, Inhibitor of CYP3A4;Inhibitor of MET proto-oncogene; receptor tyrosine kinaseCas Number: 1173699-31-4Formula: C23H22FN7O3 Molecular Weight: 463.46IUPAC Name: 6-[(1R)-1-[8-fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5-oneSMILES: CC(C1=NN=C2N1C=C(C=C2F)C3=CN(N=C3)C)N4C=CC5=C(C4=O)C=C(C=N5)OCCOCInChIKey: DWHXUGDWKAIASB-CQSZACIVSA-NInChI: show more Synonyms: 1,6-Naphthyridin-5(6H)-one, 6-((1R)-1-(8-fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo(4,3-a)pyridin-3-yl)ethyl)...
-
AfatinibCas Number: 439081-18-2Formula: C24H25ClFN5O3 Molecular Weight: 485.94IUPAC Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamideSMILES: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4InChIKey: ULXXDDBFHOBEHA-CWDCEQMOSA-NInChI: show more Synonyms: BIBW2992 | (2E)-N-(4-(3-chloro-4-fluoroanilino)-7-(((3S)-oxolan-3-yl)oxy)quinoxazolin-6-yl)-4-(dimethylamino)but-2-en...
-
Afatinib dimaleate, Receptor protein-tyrosine kinase erbB-4 inhibitorCas Number: 850140-73-7 Compound CID: 15606394Formula: C32H33ClFN5O11 Molecular Weight: 718.08IUPAC Name: (Z)-but-2-enedioic acid;(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamideSMILES: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)OInChIKey: USNRYVNRPYXCSP-JUGPPOIOSA-NInChI: show more Synonyms: BIBW2992 DiMaleate | (2E)-N-(4-[(3-chloro-4-fluorophenyl)amino]-7-{[(3S)-tetrahydrofuran-3-yl]oxy}quinazolin-6-yl)-4-...
-
AfatinibCas Number: 439081-18-2Formula: C24H25ClFN5O3 Molecular Weight: 485.94IUPAC Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamideSMILES: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4InChIKey: ULXXDDBFHOBEHA-CWDCEQMOSA-NInChI: show more Synonyms: (2E)-N-(4-(3-chloro-4-fluoroanilino)-7-(((3S)-oxolan-3-yl)oxy)quinoxazolin-6-yl)-4-(dimethylamino)but-2-enamide | AFA...
-
Altiratinib, Neurotrophic tyrosine kinase receptor inhibitorCas Number: 1345847-93-9Formula: C26H21F3N4O4 Molecular Weight: 510.46IUPAC Name: 1-N'-[4-[2-(cyclopropanecarbonylamino)pyridin-4-yl]oxy-2,5-difluorophenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideSMILES: C1CC1C(=O)NC2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F)FInChIKey: GNNDEPIMDAZHRQ-UHFFFAOYSA-NInChI: show more Synonyms: NSC784590 | NSC-784590 | DCC-270 | J-690136 | Q27074416 | Altiratinib(DCC-2701) | s6412 | GNNDEPIMDAZHRQ-UHFFFAOYSA-N...
