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Rozanolixizumab (anti-FCGRT) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to FCGRT, >95%, high purity, Human IgG4SP, Antibody of Fc fragment of IgG receptor and transporter, Antibody of Fc fragment of IgG receptor and transporter

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab170571
Grouped product items
SKU Size
Availability
Price Qty
Ab170571-100μg
100μg
10
$79.90
Ab170571-1mg
1mg
4
$357.90
Ab170571-5mg
5mg
1
$717.90
Ab170571-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,167.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Rozanolixizumab (anti-FCGRT) - Primary antibody, for ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt various applications, specific to FCGRT, >95%, high purity, Human IgG4SP, Antibody of Fc fragment of IgG receptor and transporter
Synonyms FcRn | IgG Fc fragment receptor transporter alpha chain | Neonatal Fc receptor
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity FCGRT
Application ELISA,Functional Assay,Kinetics (BLI),Kinetics (SPR),Flow Cyt
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of Fc fragment of IgG receptor and transporter
Product Description

Rozanolixizumab (anti-FCGRT) , a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases.

Purity:

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.8 kDa (Light Chain) & 51.8 kDa (Heavy Chain), under reducing conditions; 174.5 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1584645-37-3

Associated Targets(Human)

FCGRT Tclin IgG receptor FcRn large subunit p51 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Rozanolixizumab (anti-FCGRT) (Ab170571) - ELISA
Immobilized Rozanolixizumab (anti-FCGRT) (Ab170571) at 2 μg/mL can bind FcRn(FCGRT)-chis+FcRn(B2M)-Strep II with the EC₅₀ of 10.29 ng/mL.

Rozanolixizumab (anti-FCGRT) (Ab170571) - SEC
The purity of Rozanolixizumab (anti-FCGRT) (Ab170571) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303690 Certificate of Analysis Mar 25, 2024 Ab170571
ZJ24F0303689 Certificate of Analysis Mar 25, 2024 Ab170571
ZJ24F0303688 Certificate of Analysis Mar 25, 2024 Ab170571

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