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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182892-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$89.90
|
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Ab182892-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$419.90
|
|
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Ab182892-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,089.90
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Ab182892-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,749.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Urabrelimab (anti-CD47) - Primary antibody, specific to CD47, Human IgG4SP |
|---|---|
| Synonyms | Antigen identified by monoclonal antibody 1D8 antibody | Antigenic surface determinant protein OA3 antibody | CD 47 antibody | CD47 antibody | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody | CD47 antigen antibody | CD47 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD47 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Urabrelimab (anti-CD47) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.46 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2249722-58-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Urabrelimab (anti-CD47) (Ab182892) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling CD47 (red) with Urabrelimab (anti-CD47) (Ab182892). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Urabrelimab (anti-CD47) (Ab182892) - ELISA
Immobilized Recombinant Human CD47 protein (rp144028) at 1.0 μg/mL can bind Urabrelimab (anti-CD47) (Ab182892) with the EC
₅₀
of 27.65 ng/mL.
Urabrelimab (anti-CD47) (Ab182892) - SEC
The purity of Urabrelimab (anti-CD47) (Ab182892) is more than 95% verified by HPLC.
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