Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab209891-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$49.90
|
|
|
Ab209891-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$249.90
|
|
|
Ab209891-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$639.90
|
|
|
Ab209891-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,029.90
|
|
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | CC-90002 (anti-CD47) - Primary antibody, specific to CD47, Human IgG4SP |
|---|---|
| Synonyms | Antigen identified by monoclonal antibody 1D8 antibody | Antigenic surface determinant protein OA3 antibody | CD 47 antibody | CD47 antibody | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody | CD47 antigen antibody | CD47 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, bind |
| Host species | Human |
| Specificity | CD47 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
CC-90002 (anti-CD47) is a humanized monoclonal antibody (mAb) targeting CD47. It can be used for the research of hematologic malignancies and solid tumors. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
CC-90002 (anti-CD47) (Ab209891) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD47 with CC-90002 (anti-CD47) (Ab209891) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
CC-90002 (anti-CD47) (Ab209891) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD47 (red) with CC-90002 (anti-CD47) (Ab209891) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
CC-90002 (anti-CD47) (Ab209891) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling CD47 (red) with CC-90002 (anti-CD47) (Ab209891) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
CC-90002 (anti-CD47) (Ab209891) - ELISA
Immobilized Recombinant Human CD47 protein (rp144028) at 1.0 μg/mL can bind CC-90002 (anti-CD47) (Ab209891) with the EC50 of 17.78 ng/mL.
CC-90002 (anti-CD47) (Ab209891) - SEC
The purity of CC-90002 (anti-CD47) (Ab209891) is more than 95% verified by HPLC.
Starting at $89.90
Starting at $49.90
Starting at $49.90
Starting at $49.90
Starting at $26.90
Starting at $59.90
Starting at $56.90
Starting at $99.90
Starting at $59.90
Starting at $26.90