This is a demo store. No orders will be fulfilled.

CM-24 (anti-CEACAM1) - Primary antibody, specific to CEACAM1, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177864
Grouped product items
SKU Size
Availability
Price Qty
Ab177864-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab177864-1mg
1mg
5
$519.90
Ab177864-5mg
5mg
1
$1,399.90
Ab177864-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name CM-24 (anti-CEACAM1) - Primary antibody, specific to CEACAM1, >95%, high purity, Human IgG1
Synonyms Antigen CD66 antibody | BGP 1 antibody | BGP antibody | BGP-1 antibody | BGPI antibody | Biliary glycoprotein 1 antibody | Biliary glycoprotein adhesion molecule antibody | Biliary glycoprotein antibody | Carcinoembryonic antigen related cell adhesion mol
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CEACAM1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

CM-24 (anti-CEACAM1) is a humanized monoclonal immunoglobulin G4 (IgG4) antibody targeting CEACAM1 and CD66a, with potential immunomodulating and antineoplastic activities. It blocks the binding of CEACAM1-expressing cancer cells to CEACAM1-expressing immune cells and abrogates CEACAM1-mediated immunosuppression.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.5 kDa (Light Chain) & 49.7kDa (Heavy Chain), under reducing conditions; 196.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

CEACAM1 Tbio Carcinoembryonic antigen-related cell adhesion molecule 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

CM-24 (anti-CEACAM1) (Ab177864) - Flow Cytometry
Flow Cytometry analysis of HT-29 cells labelling CEACAM1 (red) with CM-24 (anti-CEACAM1) (Ab177864). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

CM-24 (anti-CEACAM1) (Ab177864) - Flow Cytometry
Flow Cytometry analysis of HepG2 cells labelling CEACAM1 (red) with CM-24 (anti-CEACAM1) (Ab177864). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

CM-24 (anti-CEACAM1) (Ab177864) - SEC
The purity of CM-24 (anti-CEACAM1) (Ab177864) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202224 Certificate of Analysis Dec 28, 2023 Ab177864
ZJ23F1202223 Certificate of Analysis Dec 28, 2023 Ab177864

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.