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Anetumab (anti-Mesothelin) - Primary antibody, specific to MSLN, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab190133
Grouped product items
SKU Size
Availability
Price Qty
Ab190133-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab190133-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab190133-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$769.90
Ab190133-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,159.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Anetumab (anti-Mesothelin) - Primary antibody, specific to MSLN, Human IgG1
Synonyms soluble MPF mesothelin related protein | CAK1 antibody | CAK 1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factor antibody | SMR | Pre-pro-megakaryocyte-potentiating factor | MSLN | Mesothelin antibody | Mesotheli
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MSLN
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Anetumab (anti-Mesothelin) is an anti-mesothelin (MSLN) antibody. MSLN is a tumor-associated antigen. Anetumab (anti-Mesothelin) can be used to synthesis Anetumab ravtansine, a MSLN-targeting antibody-drug conjugate (ADC). Anetumab (anti-Mesothelin) can be used for the research of malignant tumor.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
≤1.0EU/mg
Protein Function
Membrane-anchored forms may play a role in cellular adhesion.
Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.

Product Properties

Isotype Human IgG1
Light Chain Type lambdaC2
SDS-PAGE 143.8 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1954758-84-9

Associated Targets(Human)

MSLN Tbio Mesothelin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Anetumab (anti-Mesothelin) (Ab190133) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling Mesothelin (red) with Anetumab (anti-Mesothelin) (Ab190133). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Anetumab (anti-Mesothelin) (Ab190133) - ELISA
Immobilized Recombinant Human Mesothelin-huFc(6-7) protein at 2.0 μg/mL can bind Anetumab (anti-Mesothelin) (Ab190133) with the EC ₅₀  of 55.81 ng/mL.

Anetumab (anti-Mesothelin) (Ab190133) - SEC
The purity of Anetumab (anti-Mesothelin) (Ab190133) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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