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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab190133-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$69.90
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Ab190133-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$329.90
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Ab190133-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$769.90
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Ab190133-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,159.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Anetumab (anti-Mesothelin) - Primary antibody, specific to MSLN, Human IgG1 |
|---|---|
| Synonyms | soluble MPF mesothelin related protein | CAK1 antibody | CAK 1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factor antibody | SMR | Pre-pro-megakaryocyte-potentiating factor | MSLN | Mesothelin antibody | Mesotheli |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MSLN |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Anetumab (anti-Mesothelin) is an anti-mesothelin (MSLN) antibody. MSLN is a tumor-associated antigen. Anetumab (anti-Mesothelin) can be used to synthesis Anetumab ravtansine, a MSLN-targeting antibody-drug conjugate (ADC). Anetumab (anti-Mesothelin) can be used for the research of malignant tumor. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambdaC2 |
| SDS-PAGE | 143.8 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1954758-84-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Anetumab (anti-Mesothelin) (Ab190133) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling Mesothelin (red) with Anetumab (anti-Mesothelin) (Ab190133). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Anetumab (anti-Mesothelin) (Ab190133) - ELISA
Immobilized Recombinant Human Mesothelin-huFc(6-7) protein at 2.0 μg/mL can bind Anetumab (anti-Mesothelin) (Ab190133) with the EC
₅₀
of 55.81 ng/mL.
Anetumab (anti-Mesothelin) (Ab190133) - SEC
The purity of Anetumab (anti-Mesothelin) (Ab190133) is more than 95% verified by HPLC.
Starting at $49.90
Starting at $109.90