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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209789-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209789-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$509.90
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Ab209789-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209789-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | BMS-986148 (anti-Mesothelin) - Primary antibody, specific to MSLN |
|---|---|
| Synonyms | CAK 1 antibody | CAK1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factor antibody | Mesothelin antibody | Mesothelin isoform 1 precursor antibody | MPF antibody | Msln antibody | MSLN_HUMAN antibody | Pre pro mega |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. |
| Host species | Human |
| Specificity | MSLN |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
BMS-986148 (anti-Mesothelin) is a fully human IgG1 monoclonal antibody targeting mesothelin. It is used to synthesize antibody-drug conjugate (ADC). It has potential multimodal therapeutic strategies in patients with advanced solid tumors. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 144.46 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
BMS-986148 (anti-Mesothelin) (Ab209789) - ELISA
Immobilized Recombinant Mesothelin ECD-huFc-CHO-K protein at 2.0 μg/mL can bind BMS-986148 (anti-Mesothelin) (Ab209789), with the EC50 is 60.84 ng/mL.
BMS-986148 (anti-Mesothelin) (Ab209789) - SEC
The purity of BMS-986148 (anti-Mesothelin) (Ab209789) is more than 95% verified by HPLC.
Starting at $69.90
Starting at $49.90