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BMS-986148 (anti-Mesothelin) - Primary antibody, specific to MSLN

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209789
Grouped product items
SKU Size
Availability
Price Qty
Ab209789-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209789-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209789-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209789-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name BMS-986148 (anti-Mesothelin) - Primary antibody, specific to MSLN
Synonyms CAK 1 antibody | CAK1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factor antibody | Mesothelin antibody | Mesothelin isoform 1 precursor antibody | MPF antibody | Msln antibody | MSLN_HUMAN antibody | Pre pro mega
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Host species Human
Specificity MSLN
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

BMS-986148 (anti-Mesothelin) is a fully human IgG1 monoclonal antibody targeting mesothelin. It is used to synthesize antibody-drug conjugate (ADC). It has potential multimodal therapeutic strategies in patients with advanced solid tumors.

Product Properties

Light Chain Type kappa
SDS-PAGE 144.46 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

MSLN Tbio Mesothelin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

BMS-986148 (anti-Mesothelin) (Ab209789) - ELISA
Immobilized Recombinant Mesothelin ECD-huFc-CHO-K protein at 2.0 μg/mL can bind BMS-986148 (anti-Mesothelin) (Ab209789), with the EC50 is 60.84 ng/mL.

BMS-986148 (anti-Mesothelin) (Ab209789) - SEC
The purity of BMS-986148 (anti-Mesothelin) (Ab209789) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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