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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170485-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab170485-1mg
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1mg |
5
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$239.90
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Ab170485-5mg
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5mg |
1
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$619.90
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Ab170485-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$989.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Amatuximab (anti-MSLN) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to MSLN, >95%, high purity, Human IgG1, INHIBITOR of Mesothelin inhibitor |
|---|---|
| Synonyms | Amatuximab | CAK 1 antibody | CAK1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factorantibody | Mesothelin antibody | Mesothelin isoform 1 precursorantibody | MPF antibody | Msln antibody | MSLN_HUMAN antibody | P |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MSLN |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Mesothelin inhibitor |
| Product Description |
Amatuximab (anti-MSLN) is a recombinant monoclonal antibody that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 175.6 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 931402-35-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Amatuximab (anti-MSLN) (Ab170485) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling MSLN (red) with Amatuximab (anti-MSLN) (Ab170485). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Amatuximab (anti-MSLN) (Ab170485) - SEC
The purity of Amatuximab (anti-MSLN) (Ab170485) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 08, 2023 | Ab170485 | |
| Certificate of Analysis | Nov 08, 2023 | Ab170485 |
Starting at $109.90
Starting at $69.90