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Amatuximab (anti-MSLN) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to MSLN, >95%, high purity, Human IgG1, INHIBITOR of Mesothelin inhibitor, INHIBITOR of Mesothelin inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170485
Grouped product items
SKU Size
Availability
Price Qty
Ab170485-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170485-1mg
1mg
5
$239.90
Ab170485-5mg
5mg
1
$619.90
Ab170485-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$989.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Amatuximab (anti-MSLN) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to MSLN, >95%, high purity, Human IgG1, INHIBITOR of Mesothelin inhibitor
Synonyms Amatuximab | CAK 1 antibody | CAK1 antibody | CAK1 antigen antibody | cleaved form antibody | Megakaryocyte potentiating factorantibody | Mesothelin antibody | Mesothelin isoform 1 precursorantibody | MPF antibody | Msln antibody | MSLN_HUMAN antibody | P
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MSLN
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Mesothelin inhibitor
Product Description

Amatuximab (anti-MSLN) is a recombinant monoclonal antibody that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.9 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 175.6 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 931402-35-6

Associated Targets(Human)

MSLN Tbio Mesothelin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Amatuximab (anti-MSLN) (Ab170485) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling MSLN (red) with Amatuximab (anti-MSLN) (Ab170485). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Amatuximab (anti-MSLN) (Ab170485) - SEC
The purity of Amatuximab (anti-MSLN) (Ab170485) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101558 Certificate of Analysis Nov 08, 2023 Ab170485
ZJ23F1101559 Certificate of Analysis Nov 08, 2023 Ab170485

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