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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170548-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$89.90
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Ab170548-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$429.90
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Ab170548-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$837.90
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Ab170548-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,254.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Brentuximab (anti-TNFRSF8) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF8, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | CD30L receptor | Ki-1 antigen | Lymphocyte activation antigen CD30 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TNFRSF8 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Brentuximab (anti-TNFRSF8) is a chimeric antibody targeting CD30. Brentuximab can be used for the research of emerging targeted therapies. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 28.0 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 172.2 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2088770-90-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Brentuximab (anti-TNFRSF8) (Ab170548) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling TNFRSF8 (red) with Brentuximab (anti-TNFRSF8) (Ab170548). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Brentuximab (anti-TNFRSF8) (Ab170548) - SEC
The purity of Brentuximab (anti-TNFRSF8) (Ab170548) is more than 95% verified by HPLC.
Brentuximab (anti-TNFRSF8) (Ab170548) - ELISA
Immobilized huCD30-his 2 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC₅₀ of 6.00 ng/mL.
Brentuximab (anti-TNFRSF8) (Ab170548) - ELISA
Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Aug 30, 2023 | Ab170548 | |
| Certificate of Analysis | Aug 30, 2023 | Ab170548 |
Starting at $22.90
Starting at $66.90
Starting at $93.90