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Brentuximab (anti-TNFRSF8) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF8, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170548
Grouped product items
SKU Size
Availability
Price Qty
Ab170548-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
Ab170548-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$429.90
Ab170548-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$837.90
Ab170548-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,254.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Brentuximab (anti-TNFRSF8) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF8, >95%, high purity, Human IgG1
Synonyms CD30L receptor | Ki-1 antigen | Lymphocyte activation antigen CD30
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF8
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Brentuximab (anti-TNFRSF8) is a chimeric antibody targeting CD30. Brentuximab can be used for the research of emerging targeted therapies.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 28.0 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 172.2 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2088770-90-3

Associated Targets(Human)

TNFRSF8 Tclin Tumor necrosis factor receptor superfamily member 8 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Brentuximab (anti-TNFRSF8) (Ab170548) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling TNFRSF8 (red) with Brentuximab (anti-TNFRSF8) (Ab170548). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Brentuximab (anti-TNFRSF8) (Ab170548) - SEC
The purity of Brentuximab (anti-TNFRSF8) (Ab170548) is more than 95% verified by HPLC.

Brentuximab (anti-TNFRSF8) (Ab170548) - ELISA
Immobilized huCD30-his 2 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC₅₀ of 6.00 ng/mL.

Brentuximab (anti-TNFRSF8) (Ab170548) - ELISA
Immobilized Recombinant Human CD30 Protein (rp169577) at 1.0 μg/mL can bind Brentuximab (anti-TNFRSF8) (Ab170548) with the EC50 of 119.9 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0800942 Certificate of Analysis Aug 30, 2023 Ab170548
ZJ23F0800938 Certificate of Analysis Aug 30, 2023 Ab170548

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