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Bemarituzumab (anti-FGFR2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to FGFR2, >95%, high purity, Human IgG1, Antibody of Fc fragment of IgG receptor IIIa;Antibody of fibrobl, Antibody of Fc fragment of IgG receptor IIIa;Antibody of fibroblast growth factor receptor 2

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170514
Grouped product items
SKU Size
Availability
Price Qty
Ab170514-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170514-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$240.90
Ab170514-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$588.90
Ab170514-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$987.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Bemarituzumab (anti-FGFR2) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to FGFR2, >95%, high purity, Human IgG1, Antibody of Fc fragment of IgG receptor IIIa;Antibody of fibrobl
Synonyms EC 2.7.10.1 | FGFR-2 | Keratinocyte growth factor receptor | KGFR | K-sam
Specifications & Purity Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), Lot by Lot
Host species Human
Specificity FGFR2
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of Fc fragment of IgG receptor IIIa;Antibody of fibroblast growth factor receptor 2
Product Description

Bemarituzumab (anti-FGFR2) is a recombinant monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.5 kDa (Light Chain) & 50.6 kDa (Heavy Chain), under reducing conditions; 171.4 kDa, under non-reducing conditions.
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration Lot by Lot
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1952272-74-0

Associated Targets(Human)

FGFR2 Tclin Fibroblast growth factor receptor 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
FCGR3A Tclin Low affinity immunoglobulin gamma Fc region receptor III-A (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
FGFR2 Tclin Fibroblast growth factor receptor 2 (3405 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FCGR3A Tclin Low affinity immunoglobulin gamma Fc region receptor III-A (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Bemarituzumab (anti-FGFR2) (Ab170514) - SEC
The purity of Bemarituzumab (anti-FGFR2) (Ab170514) is more than 95% verified by HPLC.

Bemarituzumab (anti-FGFR2) (Ab170514) - ELISA
Immobilized hu-FGFR2-β-IIIb-ECD-His 2 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC₅₀ of 13.35 ng/mL.


Bemarituzumab (anti-FGFR2) (Ab170514) - ELISA
Immobilized Recombinant Human FGFR2 alpha (IIIb) Protein (rp183618) at 1.0 μg/mL can bind Bemarituzumab (anti-FGFR2) (Ab170514) with the EC₅₀ of 22.7 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0901133 Certificate of Analysis Sep 24, 2023 Ab170514
ZJ23F0901132 Certificate of Analysis Sep 24, 2023 Ab170514

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