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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175456-100μg
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100μg |
10
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$59.90
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Ab175456-1mg
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1mg |
4
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$259.90
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Ab175456-5mg
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5mg |
1
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$749.90
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Ab175456-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,189.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Apitegromab (anti-GDF8) - Primary antibody, specific to MSTN, >95%, high purity, Human IgG4SP, INHIBITOR of Growth/differentiation factor 8 inhibitor |
|---|---|
| Synonyms | GDF 8 antibody | GDF-8 antibody | GDF8 antibody | GDF8_HUMAN antibody | Growth differentiation factor 8 antibody | Growth/differentiation factor 8 antibody | MSLHP antibody | MSTN antibody | Myostatin antibody | OTTHUMP00000163498 antibody | GDF8 | GDF-8 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MSTN |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Growth/differentiation factor 8 inhibitor |
| Product Description |
Apitegromab (anti-GDF8) is an anti-promyostatin monoclonal antibody. Apitegromab (anti-GDF8) can be used for the research of neuromuscular disease including spinal muscular atrophy. |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | lambda |
| SDS-PAGE | 27.9 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 187.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2278276-46-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Apitegromab (anti-GDF8) (Ab175456) - SEC
The purity of Apitegromab (anti-GDF8) (Ab175456) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 30, 2024 | Ab175456 | |
| Certificate of Analysis | Apr 30, 2024 | Ab175456 | |
| Certificate of Analysis | Apr 30, 2024 | Ab175456 |
Starting at $109.90
Starting at $49.90
Starting at $109.90