This is a demo store. No orders will be fulfilled.

 
Call +1 (833) 552-7181 or Contact us
Toggle Nav
My Cart
Search
Advanced Search
Menu
Account
Settings
྾
main product photo

Domagrozumab (anti-GDF8) - Primary antibody, specific to MSTN, Human IgG1, INHIBITOR of Growth/differentiation factor 8 inhibitor, INHIBITOR of Growth/differentiation factor 8 inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175511
Grouped product items
SKU Size
Availability
 Price Qty
Ab175511-100μg
100μg
10
$109.90
Ab175511-1mg
1mg
4
$519.90
Ab175511-5mg
5mg
1
$1,399.90
Ab175511-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: MSTN
Accession#:O14793 (6) GDF8 (5) Gene ID:2660 (6) Myostatin (3)

Basic Description

Product Name Domagrozumab (anti-GDF8) - Primary antibody, specific to MSTN, Human IgG1, INHIBITOR of Growth/differentiation factor 8 inhibitor
Synonyms GDF 8 antibody | GDF-8 antibody | GDF8 antibody | GDF8_HUMAN antibody | Growth differentiation factor 8 antibody | Growth/differentiation factor 8 antibody | MSLHP antibody | MSTN antibody | Myostatin antibody | OTTHUMP00000163498 antibody | GDF-8 | GDF8
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MSTN
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Growth/differentiation factor 8 inhibitor
Product Description

Domagrozumab (anti-GDF8) is an anti-myostatin humanized monoclonal antibody with a KD value of 2.6 pM for human myostatin. Domagrozumab (anti-GDF8) induces muscle anabolic activity. Domagrozumab (anti-GDF8) can be used in research of duchenne muscular dystrophy (DMD).
Purity≥95% (SDS-PAGE&SEC)
Endotoxin Level < 0.01EU/μg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 28.8 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 204.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS 1629605-31-7

Associated Targets(Human)

MSTN Tclin Growth/differentiation factor 8 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Domagrozumab (anti-GDF8) (Ab175511) - Flow Cytometry
pLVX-puro-SYMX01-Domagrozumab-FL-HEK293 cells were stained with Domagrozumab (anti-GDF8) (Ab175511) and negative control protein respectively, washed and then followed by PE and analyzed with the FACS EC₅₀ is 36.63 μg/mL.

Domagrozumab (anti-GDF8) (Ab175511) - SEC
The purity of Domagrozumab (anti-GDF8) (Ab175511) is more than 95% verified by HPLC.

Domagrozumab (anti-GDF8) (Ab175511) - ELISA
Immobilized Recombinant human GDF8/Myostatin protein (rp156335) at 1.0 μg/mL can bind Domagrozumab (anti-GDF8) (Ab175511) with the EC50 of 33.4 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0708310 Certificate of Analysis Jul 16, 2024 Ab175511
ZJ24F0708309 Certificate of Analysis Jul 16, 2024 Ab175511
ZJ24F0708308 Certificate of Analysis Jul 16, 2024 Ab175511

Related Products

  1. Human IgG1-kappa (FITC), anti-Spike RBD
    Human IgG1-kappa (FITC), anti-Spike RBD

    Starting at $29.90

    Wish List Compare
  2. Human IgG1-kappa (AF700), anti-Spike RBD
    Human IgG1-kappa (AF700), anti-Spike RBD

    Starting at $59.90

    Wish List Compare
  3. Human IgG1-kappa (Biotin), anti-Spike RBD
    Human IgG1-kappa (Biotin), anti-Spike RBD

    Starting at $19.90

    Wish List Compare
  4. Human IgG (AF700)
    Human IgG (AF700)

    Starting at $39.90

    Wish List Compare
  5. Goat Anti-Human IgG Fc (TRITC)
    Goat Anti-Human IgG Fc (TRITC)

    Starting at $10.90

    Wish List Compare
  6. Centrose patent anti-dysadherin (anti-Dysadherin)
    Centrose patent anti-dysadherin (anti-Dysadherin)

    Starting at $109.90

    Wish List Compare
  7. Goat Anti-Human IgG Fc (AF647)
    Goat Anti-Human IgG Fc (AF647)

    Starting at $10.90

    Wish List Compare
  8. Goat Anti-Human IgG Fc (Biotin)
    Goat Anti-Human IgG Fc (Biotin)

    Starting at $10.90

    Wish List Compare
  9. Human IgG1-kappa (APC), anti-Spike RBD
    Human IgG1-kappa (APC), anti-Spike RBD

    Starting at $21.90

    Wish List Compare
  10. Goat Anti-Human IgG Fc (FITC)
    Goat Anti-Human IgG Fc (FITC)

    Starting at $10.90

    Wish List Compare
  11. Goat Anti-Human IgG (AF488)
    Goat Anti-Human IgG (AF488)

    Starting at $10.90

    Wish List Compare
  12. Goat Anti-Human IgG Fc (AF700)
    Goat Anti-Human IgG Fc (AF700)

    Starting at $10.90

    Wish List Compare
  13. Goat Anti-Human IgG Fc (Cy5)
    Goat Anti-Human IgG Fc (Cy5)

    Starting at $10.90

    Wish List Compare
  14. Human IgG (AF405)
    Human IgG (AF405)

    Starting at $39.90

    Wish List Compare
  15. Human IgG (AF488)
    Human IgG (AF488)

    Starting at $39.90

    Wish List Compare
  16. Goat Anti-Human IgG Fc (AF555)
    Goat Anti-Human IgG Fc (AF555)

    Starting at $10.90

    Wish List Compare
  17. Human IgG (AF647)
    Human IgG (AF647)

    Starting at $39.90

    Wish List Compare
  18. Human IgG (AF555)
    Human IgG (AF555)

    Starting at $39.90

    Wish List Compare
  19. Human IgG1-kappa (AF555), anti-Spike RBD
    Human IgG1-kappa (AF555), anti-Spike RBD

    Starting at $49.90

    Wish List Compare
  20. Goat Anti-Human IgG Fc (AF405)
    Goat Anti-Human IgG Fc (AF405)

    Starting at $10.90

    Wish List Compare

Alternative Products

  1. Trevogrumab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor
    Trevogrumab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor

    Starting at $109.90

  2. Stamulumab (anti-Myostatin)
    Stamulumab (anti-Myostatin)

    Starting at $49.90

  3. Landogrozumab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor
    Landogrozumab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor

    Starting at $69.90

  4. Apitegromab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor
    Apitegromab (anti-GDF8), INHIBITOR of Growth/differentiation factor 8 inhibitor

    Starting at $59.90

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.