Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab179373-100μg
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100μg |
10
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$109.90
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Ab179373-1mg
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1mg |
4
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$519.90
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|
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Ab179373-5mg
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5mg |
1
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$1,299.90
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|
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Ab179373-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Anrukinzumab (anti-IL-13) - Primary antibody, specific to IL13, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-13 inhibitor |
|---|---|
| Synonyms | Allergic rhinitis antibody | ALRH antibody | BHR 1 antibody | BHR1 antibody | Bronchial hyperresponsiveness 1 (bronchial asthma) antibody | IL 13 antibody | IL-13 antibody | Il13 antibody | IL13_HUMAN antibody | Interleukin 13 antibody | Interleukin-13 an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL13 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-13 inhibitor |
| Product Description |
Anrukinzumab (anti-IL-13) is a humanized anti-IL-13 monoclonal antibody. Anrukinzumab (anti-IL-13) effectively reduces lung inflammation in a cynomolgus monkey model. Anrukinzumab (anti-IL-13) can be used in studies of ulcerative colitis (UC) as well as asthma. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.38 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 910649-32-0 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Anrukinzumab (anti-IL-13) (Ab179373) - ELISA
Immobilized Recombinant Human IL-13 Protein (rp147396) at 2.0 μg/mL can bind Anrukinzumab (anti-IL-13) (Ab179373) with the EC50 of 357.7 ng/mL.
Anrukinzumab (anti-IL-13) (Ab179373) - SEC
The purity of Anrukinzumab (anti-IL-13) (Ab179373) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 08, 2024 | Ab179373 | |
| Certificate of Analysis | Apr 08, 2024 | Ab179373 | |
| Certificate of Analysis | Apr 08, 2024 | Ab179373 |
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