Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab170946-100μg
|
100μg |
10
|
$69.90
|
|
|
Ab170946-1mg
|
1mg |
4
|
$339.90
|
|
|
Ab170946-5mg
|
5mg |
1
|
$669.90
|
|
|
Ab170946-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,049.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Tralokinumab (anti-IL-13) - Primary antibody, specific to IL13, >95%, high purity, Human IgG4SP, INHIBITOR of Interleukin-13 inhibitor |
|---|---|
| Synonyms | Allergic rhinitis antibody | ALRH antibody | BHR 1 antibody | BHR1 antibody | Bronchial hyperresponsiveness 1 (bronchial asthma) antibody | IL 13 antibody | IL-13 antibody | Il13 antibody | IL13_HUMAN antibody | Interleukin 13 antibody | Interleukin-13 an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL13 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-13 inhibitor |
| Product Description |
Tralokinumab (anti-IL-13), a fully human IgG4 monoclonal antibody, specifically binds with high affinity to IL-13 alone, preventing its interaction with the receptor and subsequent downstream signalling. Tralokinumab (anti-IL-13) can be used for the research of the atopic dermatitis (AD). |
| Isotype | Human IgG4SP |
|---|---|
| Light Chain Type | lambdaC2 |
| SDS-PAGE | 27.8 kDa (Light Chain) & 51.7 kDa (Heavy Chain), under reducing conditions; 170.5 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1044515-88-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Tralokinumab (anti-IL-13) (Ab170946) - ELISA
Immobilized Tralokinumab (anti-IL-13) (Ab170946) at 2 μg/mL can bind human IL-13 protein with the EC₅₀ of 3.33 ng/mL.
Tralokinumab (anti-IL-13) (Ab170946) - SEC
The purity of Tralokinumab (anti-IL-13) (Ab170946) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 26, 2024 | Ab170946 | |
| Certificate of Analysis | Mar 26, 2024 | Ab170946 | |
| Certificate of Analysis | Mar 26, 2024 | Ab170946 |
Starting at $69.90
Starting at $59.90
Starting at $109.90
Starting at $49.90
Starting at $109.90
Starting at $109.90
Starting at $109.90
Starting at $109.90
Starting at $109.90