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Recombinant Human 4-1BB Ligand/TNFSF9 Protein

  • 表达系统: E. coli
  • Accession #: P41273
  • 蛋白标签: N-His
  • 生物活性: Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.​
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp169691-10μg
10μg 现货 Stock Image
rp169691-50μg
50μg 现货 Stock Image
rp169691-100μg
100μg 现货 Stock Image
rp169691-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human 4-1BB Ligand/TNFSF9 Protein
别名 重组人4-1BB Ligand/TNFSF9蛋白 | 重组人 4-1BB 配体/TNFSF9 蛋白
英文别名 41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | tumor necrosis factor ligand superfamily member 9
规格或纯度 Carrier Free, Bioactive, ≥95%(SDS-PAGE)
产品介绍


Purity:≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

生物活性 Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.​
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 71-254 aa
序列 MGMKHHHHHHENLYFQGSREGPELSPDDPAGLLDLRQGMFAQLVAQNVLLIDGPLSWYSDPGLAGVSLTGGLSYKEDTKELVVAKAGVYYVFFQLELRRVVAGEGSGSVSLALHLQPLRSAAGAAALALTVDLPPASSEARNSAFGFQGRLLHLSAGQRLGVHLHTEARARHAWQLTQGATVLGLFRVTPEIPAGLPSPRSE
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # P41273
来源 重组表达
预测分子量 21.7 kDa
SDS-PAGE 20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, 300mM NaCl, 3% trehalose, pH7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - ELISA

Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB Ligand/TNFSF9 Protein (rp169691) at 2.0 μg/mL can bind Human 4-1BB Ligand/TNFSF9-biotin with the EC₅₀ of 6.053 ng/mL.


Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - SDS-PAGE
2 μg/lane of Recombinant Human 4-1BB Ligand/TNFSF9 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.6 kDa.

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批号(Lot Number) 证书类型 货号
ZJ24F0809686 分析证书 rp169691
ZJ24F0809687 分析证书 rp169691
ZJ24F0809688 分析证书 rp169691

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