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Recombinant Human 4-1BB Ligand Protein

  • 表达系统: E. coli
  • Accession #: P41273
  • 蛋白标签: No tag
  • 生物活性: Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
  • 内毒素水平: <1.0 EU/μg
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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
rp142386-10μg
10μg 现货 Stock Image
rp142386-20μg
20μg 期货 Stock Image
rp142386-50μg
50μg 现货 Stock Image
rp142386-100μg
100μg 现货 Stock Image
rp142386-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human 4-1BB Ligand Protein
别名 重组人 4-1BB 配体蛋白
英文别名 41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | tumor necrosis factor ligand superfamily member 9 | TNLG5A
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity

> 95 % by SDS-PAGE and HPLC analyses. Endotoxin level is less than 1 EU/µg.


Function

4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. Cytokine that binds to TNFRSF9. This receptor contributes to the clonal expansion, survival, and development of T cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.

生物活性 Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 71-254 aa
序列 REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE
纯度 >95%(SDS-PAGE, HPLC)
蛋白标签 No tag
蛋白长度 Protein fragment
无载体 Yes
无动物源 Yes
Accession # P41273
来源 重组表达
预测分子量 19.4 kDa

储存与运输

应用 Active, SDS-PAGE
物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 使用手动除霜冷冻机,避免反复冻融循环。自收到之日起 12 个月内,-20 至 -70 ℃(以提供时为准);1 个月内,复溶后在无菌条件下 2 至 8 ℃;3 个月内,复溶后在无菌条件下 -20 至 -70 ℃。
分子类型 蛋白质

图片

Recombinant Human 4-1BB Ligand Protein (rp142386)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/mL, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.

Recombinant Human 4-1BB Ligand Protein (rp142386)-SDS-PAGE
Recombinant Human 4-1BB Ligand Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 19.4 kDa.

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批号(Lot Number) 证书类型 货号
ZJ23F0600355 分析证书 rp142386
ZJ23F0600354 分析证书 rp142386
ZJ23F0600353 分析证书 rp142386

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