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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp142386-10μg |
10μg |
现货 ![]() |
| |
| rp142386-20μg |
20μg |
期货 ![]() |
| |
| rp142386-50μg |
50μg |
现货 ![]() |
| |
| rp142386-100μg |
100μg |
现货 ![]() |
| |
| rp142386-1mg |
1mg |
期货 ![]() |
|
| 产品名称 | Recombinant Human 4-1BB Ligand Protein |
|---|---|
| 别名 | 重组人 4-1BB 配体蛋白 |
| 英文别名 | 41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | tumor necrosis factor ligand superfamily member 9 | TNLG5A |
| 规格或纯度 | ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE) |
| 产品介绍 |
Purity > 95 % by SDS-PAGE and HPLC analyses. Endotoxin level is less than 1 EU/µg. Function 4-1BBL is a member of the tumor necrosis factor (TNF) receptor family. Cytokine that binds to TNFRSF9. This receptor contributes to the clonal expansion, survival, and development of T cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.In addition, 4-1BBL expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. |
| 生物活性 | Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml. |
| 内毒素水平 | <1.0 EU/μg |
| 表达系统 | E. coli |
| 种属 | 人(Human) |
| 氨基酸 | 71-254 aa |
| 序列 | REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE |
| 纯度 | >95%(SDS-PAGE, HPLC) |
| 蛋白标签 | No tag |
| 蛋白长度 | Protein fragment |
| 无载体 | Yes |
| 无动物源 | Yes |
| Accession # | P41273 |
| 来源 | 重组表达 |
| 预测分子量 | 19.4 kDa |
| 应用 | Active, SDS-PAGE |
|---|---|
| 物理形态 | 冻干(Lyophilized) |
| 储存缓冲液 | Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4 |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃. Further dilutions should be made in appropriate buffered solutions. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 使用手动除霜冷冻机,避免反复冻融循环。自收到之日起 12 个月内,-20 至 -70 ℃(以提供时为准);1 个月内,复溶后在无菌条件下 2 至 8 ℃;3 个月内,复溶后在无菌条件下 -20 至 -70 ℃。 |
| 分子类型 | 蛋白质 |
Recombinant Human 4-1BB Ligand Protein (rp142386)-Protein Bioactivity
Fully biologically active when compared to standard. The ED₅₀ as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/mL, corresponding to a specific activity of > 1.0 × 10⁵ IU/mg.
Recombinant Human 4-1BB Ligand Protein (rp142386)-SDS-PAGE
Recombinant Human 4-1BB Ligand Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a single band at 19.4 kDa.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp142386 | |
| 分析证书 | rp142386 | |
| 分析证书 | rp142386 |