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Recombinant Human IL-21 Protein

  • 表达系统: E. coli
  • Accession #: Q9HBE4
  • 蛋白标签: N-His
  • 生物活性: Immobilized Recombinant Human IL-21R Protein (rp147505) at 2.0 μg/mL can bind Recombinant Human IL-21 Protein (rp156003) with the EC50 of 111.90 ng/mL
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp156003-10μg
10μg 现货 Stock Image
rp156003-50μg
50μg 现货 Stock Image
rp156003-100μg
100μg 现货 Stock Image
rp156003-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-21 Protein
别名 重组人IL-21蛋白 | 重组人 IL-21 蛋白
英文别名 CVID11 | IL21 | IL-21 | IL-21Za11interleukin-21 | interleukin 21 | interleukin-21 isoform | Za11
规格或纯度 Carrier Free, Bioactive, ≥95%(SDS-PAGE)
产品介绍


Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).

生物活性 Immobilized Recombinant Human IL-21R Protein (rp147505) at 2.0 μg/mL can bind Recombinant Human IL-21 Protein (rp156003) with the EC50 of 111.90 ng/mL
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 30-162 aa
序列 MGSSHHHHHHSSGLVPRGSHMQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # Q9HBE4
来源 重组表达
预测分子量 17.8 kDa
SDS-PAGE 17.3 kDa, under reducing conditions; 16.9 kDa, under non-reducing conditions

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, pH7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

图片

Recombinant Human IL-21 Protein (rp156003) - ELISA
Immobilized Recombinant Human IL-21R Protein (rp147505) at 2.0 μg/mL can bind Recombinant Human IL-21 Protein (rp156003) with the EC₅₀ of 111.90 ng/mL.

Recombinant Human IL-21 Protein (rp156003) - SDS-PAGE
2 μg/lane of Recombinant Human IL-21 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 17.3 kDa under reducing conditions and 16.9 kDa under non-reducing conditions.

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批号(Lot Number) 证书类型 货号
ZJ24F0606565 分析证书 rp156003
ZJ24F0606563 分析证书 rp156003
ZJ24F0606564 分析证书 rp156003

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