Recombinant Mouse IL-6 Protein

COA

级别和纯度:

≥96%(SDS-PAGE&HPLC)

表达系统: E. coli
Accession #: P08505
蛋白标签: No tag
生物活性: Measured in a cell proliferation assay using M-NFS-60 mouse B cell. The ED₅₀ for this effect is less than 0.4 ng/mL.
内毒素水平: <0.1 EU/μg

有货

库存信息

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库存信息

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库存信息

关闭

货号 (SKU)	包装规格	是否现货
rp154236-10μg	10μg	现货
rp154236-50μg	50μg	现货
rp154236-100μg	100μg	现货

查看相关系列

点击查看蛋白信息: IL6

Accession#:P08505 (2) Gene ID:16193 (2) IL6 (25)

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基本描述

产品名称	Recombinant Mouse IL-6 Protein
别名	重组小鼠 IL-6 蛋白
英文别名	B-cell differentiation factor \| B-cell stimulatory factor 2 \| BSF2 \| BSF-2 \| CDF \| CTL differentiation factor \| HSF \| hybridoma growth factor \| IFNB2 \| IFN-beta-2 \| IL6 \| IL-6 \| Interferon beta-2 \| interleukin 6 (interferon, beta 2) \| interleukin BSF-2 \|
规格或纯度	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, High performance, ≥96%(SDS-PAGE&HPLC)
产品介绍	Interleukin-6 (IL-6) encoded by the IL-6 gene, acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response. IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Murine IL-6 is a 21.7kDa globular protein containing 188 amino acid residues. Purity ＞96%(SDS-PAGE,HPLC) Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
生物活性	Measured in a cell proliferation assay using M-NFS-60 mouse B cell. The ED₅₀ for this effect is less than 0.4 ng/mL.
内毒素水平	<0.1 EU/μg
表达系统	E. coli
种属	小鼠(Mouse)
氨基酸	25-211 aa
序列	MFPTSQVRRGDFTEDTTPNRPVYTTSQVGGLITHVLWEIVEMRKELCNG NSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLLEYH SYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPIS NALLTDKLESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQT
纯度	＞96%(SDS-PAGE,HPLC)
蛋白标签	No tag
N-末端序列	Met
蛋白长度	Full length protein
无载体	Yes
无动物源	Yes
Accession #	P08505
来源	重组表达
预测分子量	21.7 kDa

储存与运输

物理形态	冻干(Lyophilized)
储存缓冲液	Lyophilized from a 0.2µm filtered concentrated solution in 30 mM Acetic Acid, pH 3.0, 150 m M NaCl, 3% Trehalose, 0.02% Tween-20.
复溶	1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. 2、 Reconstitute in a sterile aqueous buffer to an appropriate concentration. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions.
储存温度	-20°C储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	如需长期保存，本品应≤-20℃保存。供货时 -20 至 -70℃ 可保存 36 个月；复溶后在无菌条件下 2 至 8℃ 可保存 1 个月；复溶后在无菌条件下 -20 至 -70℃ 可保存 3 个月。请避免反复冻融循环。
分子类型	蛋白质

图片

Protein Bioactivity: Recombinant Mouse IL-6 Protein (rp154236)

Recombinant Mouse IL-6 Protein (rp154236)-Protein Bioactivity
Measured in a cell proliferation assay using M-NFS-60 mouse B cell. The ED₅₀ for this effect is typically <0.4ng/mL.

SDS-PAGE: Recombinant Mouse IL-6 Protein (rp154236)

Recombinant Mouse IL-6 Protein (rp154236)-SDS-PAGE
3μg/lane of Recombinant Mouse IL-6 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.1 kDa.

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找到7个结果

批号(Lot Number)	证书类型	货号
ZJ25F0319555	分析证书	rp154236
ZJ24F0404263	分析证书	rp154236
ZJ24F0404262	分析证书	rp154236
ZJ24F0404261	分析证书	rp154236
ZJ23F0400120	分析证书	rp154236
ZJ23F0400118	分析证书	rp154236
ZJ23F0400119	分析证书	rp154236

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Recombinant Mouse IL-6 Protein

库存信息

库存信息

库存信息

基本描述

储存与运输

图片

质检证书（CoA,COO,BSE/TSE 和分析图谱)

技术文档和文章

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