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Recombinant Mouse FGF-21 Protein

  • 表达系统: HEK293
  • Accession #: Q9JJN1
  • 蛋白标签: C-His
  • 生物活性: Measured in a cell proliferation assay using NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4-2 μg/mL in the presence of Recombinant Mouse Klotho beta.
  • 内毒素水平: <0.1 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp153968-10μg
10μg 现货 Stock Image
rp153968-50μg
50μg 现货 Stock Image
rp153968-100μg
100μg 现货 Stock Image
rp153968-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Mouse FGF-21 Protein
别名 成纤维细胞生长因子21(FGF21)重组蛋白 | 成纤维细胞生长因子21(FGF21)重组蛋白
英文别名 FGF21 | FGF-21 | fibroblast growth factor 21 | FGFL | PRO10196 | UNQ3115 | FGF21 | FGF-21 | fibroblast growth factor 21 | FGFL | PRO10196 | UNQ3115
规格或纯度 ActiBioPure™, 重组, 无动物源, Carrier Free, High performance, ≥95%(SDS-PAGE)
生化机理 Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
生物活性 Measured in a cell proliferation assay using NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4-2 μg/mL in the presence of Recombinant Mouse Klotho beta.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 小鼠(Mouse)
氨基酸 30-210 aa
序列 YPIPDSSPLLQFGGQVRQRYLYTDDDQDTEAHLEIREDGTVVGAAHRSPESLLELKALKPGVIQILGVKASRFLCQQPDGALYGSPHFDPEACSFRELLLEDGYNVYQSEAHGLPLRLPQKDSPNQDATSWGPVRFLPMPGLLHEPQDQAGFLPPEPPDVGSSDPLSMVEPLQGRSPSYASHHHHHH
蛋白标签 C-His
无载体 Yes
无动物源 Yes
Accession # Q9JJN1
来源 重组表达
预测分子量 20 kDa
SDS-PAGE 22 kDa, under reducing conditions; 22 kDa, under non-reducing conditions.

关联靶点(人)

FGF21 Tbio 成纤维细胞生长因子 21(Fibroblast growth factor 21) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 长期储存-20~-80℃(1年);复溶后建议分装,避免反复冻融。
分子类型 蛋白质

图片

Recombinant Mouse FGF-21 Protein (rp153968) - SDS-PAGE
2 μg/lane of Recombinant Mouse FGF-21 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 22 kDa due to glycosylation.

Recombinant Mouse FGF-21 Protein (rp153968) - Protein Bioactivity
Measured in a cell proliferation assay using NIH‑3T3 mouse embryonic fibroblast cells. The ED₅₀ for this effect is 23.4 ng/mL in the presence of 1.0 μg/mL Recombinant Mouse Klotho beta Protein (rp184968).

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批号(Lot Number) 证书类型 货号
ZJ25F0926872 分析证书 rp153968
ZJ25F0926871 分析证书 rp153968
ZJ25F0926870 分析证书 rp153968
ZJ25F0420485 分析证书 rp153968
ZJ25F0420486 分析证书 rp153968
ZJ25F0420487 分析证书 rp153968

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