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Recombinant Human IL-6 Protein

  • 表达系统: E. coli
  • Accession #: P05231
  • 蛋白标签: No tag
  • 生物活性: Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically less than 0.6 ng/mL.
  • 内毒素水平: <1.0 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp147615-10μg
10μg 现货 Stock Image
rp147615-25μg
25μg 现货 Stock Image
rp147615-100μg
100μg 现货 Stock Image
rp147615-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-6 Protein
别名 重组人IL-6蛋白 | 重组人白介素6蛋白 | 重组人白细胞介素6蛋白
英文别名 B-cell differentiation factor | B-cell stimulatory factor 2 | BSF2 | BSF-2 | CDF | CTL differentiation factor | HSF | hybridoma growth factor | IFNB2 | IFN-beta-2 | IL6 | IL-6 | Interferon beta-2 | interleukin 6 (interferon, beta 2) | interleukin BSF-2 |
规格或纯度 无动物源, 无载体, 生物活性, ActiBioPure™, 高性能, ≥95%(SDS-PAGE)
生化机理 Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Post-translational: N- and O-glycosylated.
产品介绍


Purity

>95% SDS-PAGE. Protein Content and Purity (typically = 95%) determined by reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm.

Additional sequence information

This product is for the mature full length protein. The signal peptide is not included.

Function

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.

Post-translational:N- and O-glycosylated.

生物活性 Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically less than 0.6 ng/mL.
内毒素水平 <1.0 EU/μg
表达系统 E. coli
种属 人(Human)
氨基酸 29-212 aa
序列 PVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
纯度 >95% SDS-PAGE
蛋白标签 No tag
无载体 Yes
无动物源 Yes
Accession # P05231
来源 重组表达
预测分子量 20.9 kDa
SDS-PAGE 20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions.

储存与运输

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from a sterile solution containing 20 mM phosphate buffer, PH7.2
复溶 After receiving lyophilized powder protein, centrifuge first, and reconstitute at 100ug/mL in sterile PBS.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 Stable for 12 months from the date of receipt of the product under proper storage andhandling conditions. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
分子类型 蛋白质

图片

Recombinant Human IL-6 Protein (rp147615) - Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically less than 0.6 ng/mL.

Recombinant Human IL-6 Protein (rp147615) - SDS-PAGE
2 μg/lane of Recombinant Human IL-6 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.6 kDa.

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批号(Lot Number) 证书类型 货号
ZJ23F1101727 分析证书 rp147615
ZJ23F1101728 分析证书 rp147615
ZJ25F0319232 分析证书 rp147615
ZJ25F0319192 分析证书 rp147615
ZJ25F0319191 分析证书 rp147615
ZJ23F0800893 分析证书 rp147615
ZJ23F0800894 分析证书 rp147615

引用文献

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