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鱼藤酮

线粒体电子传输链复合体I抑制剂。强大的NADH氧化抑制剂。
36篇引用文献 COA COA
    级别和纯度:
  • ≥95%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
R105076-1g
 1g 现货 Stock Image
R105076-5g
 5g 现货 Stock Image
R105076-25g
 25g 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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Apoptosis (7108) Autophagy (2848) Glucose Metabolism (3713) Metabolic Enzyme/Protease (4889) Mitochondrial Metabolism (119)
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基本描述

英文别名 C23H22O6 | EINECS 201-501-9 | Spectrum4_001638 | Derris resins | Liquid Derris | (1S,6R,13S)-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one | (2R,6aS,12aS)-8,9-Dimethoxy-2-(pr
规格或纯度 ≥95%
英文名称 Rotenone
生化机理 线粒体电子传输链复合物I抑制剂（IC 50值为1.7-2.2 µM）。强大的NADH氧化抑制剂（IC 50 = 3.4 nM）。抑制微管组装。诱导BRL细胞凋亡。显示出抗增殖作用。
应用 线粒体电子传递的抑制剂
储存温度 充氩
运输条件 常规运输
备注 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。
产品介绍

难溶于水,易溶于极性有机溶剂,在氯仿中溶解度最大(472g/L) ,遇碱消旋。易氧化尤其在光或碱存在下氧化快而失去杀虫活性,在干燥情况下比较稳定。对光和空气敏感， 线粒体电子传递的抑制剂
纯度 ≥95%

关联靶点（人）

MT-ND4 Tclin NADH-泛醌氧化还原酶链 4(NADH-ubiquinone oxidoreductase chain 4) (1 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
INSR Tclin Insulin receptor (5558 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
DHODH Tclin Dihydroorotate dehydrogenase (2737 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Sigmar1 Sigma opioid receptor (160 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cruzipain (33337 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cckar Cholecystokinin A receptor (90 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mapk1 MAP kinase ERK2 (650 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MT-ND1 NADH-ubiquinone oxidoreductase chain 1 (124 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Artemia salina (1320 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Helicobacter pylori (3113 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bacteroides fragilis (1445 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Micrococcus luteus (7463 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bacillus subtilis (32866 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Candida albicans (78123 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Bombyx mori (577 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Spodoptera littoralis (798 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Drosophila melanogaster (359 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Cavia porcellus (23802 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Caenorhabditis elegans (1055 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Artemia (698 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Aedes aegypti (630 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Myzus persicae (1112 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
3T3-L1 (3664 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
L5178Y (1809 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
P388 (20296 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
MC-38 (857 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
lef Anthrax lethal factor (7585 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
NDUFV1 Mitochondrial complex I; NADH oxidoreductase (130 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Npsr1 Neuropeptide S receptor (260 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BCHE Cholinesterase (8742 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Danio rerio (3092 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Drosophila (190 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Gambusia affinis (76 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

PubChem SID 504751163
EC号 201-501-9
分子类型 小分子
IIUPAC Name (1S,6R,13S)-16,17-dimethoxy-6-prop-1-en-2-yl-2,7,20-trioxapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaen-12-one
INCHI 1S/C23H22O6/c1-11(2)16-8-14-15(28-16)6-5-12-22(24)21-13-7-18(25-3)19(26-4)9-17(13)27-10-20(21)29-23(12)14/h5-7,9,16,20-21H,1,8,10H2,2-4H3/t16-,20-,21+/m1/s1
InChi Key JUVIOZPCNVVQFO-HBGVWJBISA-N
Smiles CC(=C)C1CC2=C(O1)C=CC3=C2OC4COC5=CC(=C(C=C5C4C3=O)OC)OC
Isomeric SMILES CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC
PubChem CID 6758
UN Number 2588
Packing Group I
分子量 394.42
Beilstein号 6773081

化学和物理性质

密度 1.27
敏感性 对光和空气敏感
沸点 210-220°C
熔点 159-164°C
分子量 394.400 g/mol
XLogP3 4.100
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 6
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 394.142 Da
单同位素质量Monoisotopic Mass 394.142 Da
拓扑极表面积Topological Polar Surface Area 63.200 Ų
重原子数Heavy Atom Count 29
形式电荷Formal Charge 0
复杂度Complexity 664.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 3
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS06,   GHS09
信号词 危险
危险声明

H315: 引起皮肤刺激

H319: 引起严重眼睛刺激

H335: 可能引起呼吸道刺激

H410: 对水生生物有剧毒并具有长期持续影响

H300+H330: 吞咽或吸入会致命
预防措施声明

P260: 不要吸入灰尘/烟雾/气体/雾/蒸汽/喷雾。

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P271: 仅在室外或通风良好的地方使用。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P284: 如果通风不良，请佩戴呼吸防护装置。

P391: 收集溢出物

P301+P310: 如误吞咽：立即呼叫急救中心/医生。

P302+P352: 如皮肤沾染：用水充分清洗。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P332+P313: 如发生皮肤刺激：求医/就诊。

P337+P313: 如仍觉眼刺激：求医/就诊。

P405: 密闭存放

P403+P233: 存放在通风良好的地方。保持容器密闭。

P501: 将内容物/容器处理到。。。
WGK Germany 3
Class 6.1

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到13个结果

批号(Lot Number) 证书类型 货号
G2510581 分析证书 R105076
G2510584 分析证书 R105076
G2510580 分析证书 R105076
A2511010 分析证书 R105076
A2506427 分析证书 R105076
L2424468 分析证书 R105076
G2409119 分析证书 R105076
G2409122 分析证书 R105076
I2208493 分析证书 R105076
I2208494 分析证书 R105076
I2208495 分析证书 R105076
A2423058 分析证书 R105076
A2405059 分析证书 R105076

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引用文献

1. Zhou P et al..  (2020)  A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets..  Cell Rep,  32  (6): (108020).  [PMID:32783942]
2. Alexander RK et al..  (2020)  Bmal1 integrates mitochondrial metabolism and macrophage activation..  Elife,  9  [PMID:32396064]
3. Morein D et al..  (2021)  Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer Cells..  Cells,  10  (6): [PMID:34072893]
4. Zachari M et al..  (2019)  Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform..  Dev Cell,  50  (5): (627-643.e5).  [PMID:31353311]
5. Chatterjee N et al..  (2019)  Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers..  Cell Rep,  28  (9): (2317-2330.e8).  [PMID:31461649]
6. Okamoto A et al..  (2016)  The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells..  BMC Anesthesiol,  16  (104).  [PMID:27776485]
7. Nakamura-Ishizu A et al..  (2018)  Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation..  Cell Rep,  25  (7): (1772-1785.e6).  [PMID:30428347]
8. Zhou K et al..  (2018)  VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells..  Cell Death Dis,  9  (10): (988).  [PMID:30250190]
9. Yamei Ma, Zhen Zhang, Shengchao Gao, Yue Zhan, Zihao Wei, Ying Liu.  (2023)  The efficient Congo red decolorization coupled with electricity generation via G. sulfurreducens based on microbial fuel cells.  Journal of Environmental Chemical Engineering,  11  (111296).  [10.1016/j.jece.2023.111296]
10. Xiang Liu, Bing-Ke Li, Qin-Xue Liu, Peng-Fei Li, Fei Ling, Gao-Xue Wang.  (2024)  In vivo and in vitro antiviral effect and mechanisms of rhein against nervous necrosis virus.  AQUACULTURE,  579  (740207).  [10.1016/j.aquaculture.2023.740207]
11. Xing Yan, Ming-Jun Zhu.  (2023)  Enhanced bioelectricity generation in thermophilic microbial fuel cell with lignocellulose as an electron donor by resazurin-mediated electron transfer.  BIORESOURCE TECHNOLOGY,  388  (129764).  [PMID:37722540] [10.1016/j.biortech.2023.129764]
12. Jiayuan Li, Jiahe Yu, Jianyou Guo, Jinfeng Liu, Guohui Wan, Xiaojia Wei, Xue Yang, Jinli Shi.  (2023)  Nardostachys jatamansi and levodopa combination alleviates Parkinson’s disease symptoms in rats through activation of Nrf2 and inhibition of NLRP3 signaling pathways.  PHARMACEUTICAL BIOLOGY,  61  (1): (1175-1185).  [PMID:37559448] [10.1080/13880209.2023.2244176]
13. Xian-Xian Ji, Yu-Long Liu, Xin-Yue Chang, Rui-Long Li, Fei Ye, Liu Yang, Ying Fu.  (2023)  An electrochemical sensor derived from Cu-BTB MOF for the efficient detection of diflubenzuron in food and environmental samples.  FOOD CHEMISTRY,  428  (136802).  [PMID:37421661] [10.1016/j.foodchem.2023.136802]
14. Shengli Shi, Xinsha Zhang, Xianbin Liu, Zhen Chen, Hewen Tang, Dongbao Hu, Hongmei Li.  (2023)  GC-MS Analysis of the Essential Oil from Seseli mairei H. Wolff (Apiaceae) Roots and Their Nematicidal Activity.  MOLECULES,  28  (5): (2205).  [PMID:36903449] [10.3390/molecules28052205]
15. Shunzhang Chen, Junyuan Gong, Yanxia Cheng, Yuqi Guo, Feize Li, Tu Lan, Yuanyou Yang, Jijun Yang, Ning Liu, Jiali Liao.  (2024)  The biochemical behavior and mechanism of uranium(Ⅵ) bioreduction induced by natural Bacillus thuringiensis.  Journal of Environmental Sciences,  136  (372).  [PMID:37923447] [10.1016/j.jes.2022.12.001]
16. Li-hua Bian, Zi-wei Yao, Zhe-yi Wang, Xiao-mei Wang, Qiu-yu Li, Xue Yang, Jia-yuan Li, Xiao-jia Wei, Guo-hui Wan, Yu-qing Wang, Jin-li Shi, Jian-you Guo.  (2022)  Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways.  BIOMEDICINE & PHARMACOTHERAPY,  153  (113269).  [PMID:35728354] [10.1016/j.biopha.2022.113269]
17. Wenyu Xin, Ming Jing, Junjie Yang, Meiling Wang, Guige Hou, Qiaoyun Wang, Leiming Zhang, Chunhua Wang.  (2021)  Baicalein Exerts Anti-Neuroinflammatory Effects by Inhibiting the TLR4-ROS /NF-κB-NLRP3 Inflammasome.  Natural Product Communications,  [10.1177/1934578X211011385]
18. Zhuoheng Zhong, Shengzhi Liu, Songling Han, Yaohan Li, Minglei Tao, Amin Liu, Qiang He, Sixue Chen, Criag Dufresne, Wei Zhu, Jingkui Tian.  (2021)  Integrative omic analysis reveals the improvement of alkaloid accumulation by ultraviolet-B radiation and its upstream regulation in Catharanthus roseus.  INDUSTRIAL CROPS AND PRODUCTS,  166  (113448).  [10.1016/j.indcrop.2021.113448]
19. Bangrong Cai, Mengya Liu, Jinxing Li, Dujuan Xu, Jiansheng Li.  (2021)  Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.  FOOD AND CHEMICAL TOXICOLOGY,  150  (112050).  [PMID:33577944] [10.1016/j.fct.2021.112050]
20. Lijia Pan, Litong Nie, Sheng Yao, Aiwei Bi, Yang Ye, Yeming Wu, Zhen Tan, Zhixiang Wu.  (2020)  Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species‑mediated apoptosis by targeting the electron transport chain.  INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE,  46  (6): (2137-2149).  [PMID:33125107] [10.3892/ijmm.2020.4745]
21. Zhen-Ni Yang, Ya-Nan Hou, Bo Zhang, Hao-Yi Cheng, Yang-Chun Yong, Wen-Zong Liu, Jing-Long Han, Shuang-Jiang Liu, Ai-Jie Wang.  (2020)  Insights into palladium nanoparticles produced by Shewanella oneidensis MR-1: Roles of NADH dehydrogenases and hydrogenases.  ENVIRONMENTAL RESEARCH,  191  (110196).  [PMID:32919957] [10.1016/j.envres.2020.110196]
22. Tingting Wu, Xianying Fang, Jiahui Xu, Yan Jiang, Fuliang Cao, Linguo Zhao.  (2020)  Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson’s Disease.  MOLECULES,  25  (17): (3976).  [PMID:32878312] [10.3390/molecules25173976]
23. Tian Li, Li Tu, Ran Gu, Xiu-Lin Yang, Xiu-Juan Liu, Gui-Ping Zhang, Qian Wang, Yi-Pin Ren, Bing-Jin Wang, Jin-Yong Tian.  (2020)  Neuroprotection of GLP-1/GIP receptor agonist via inhibition of mitochondrial stress by AKT/JNK pathway in a Parkinson's disease model.  LIFE SCIENCES,  256  (117824).  [PMID:32445758] [10.1016/j.lfs.2020.117824]
24. Chen Ying, Li Rui, Zhu Yuqi, Zhong Sixia, Qian Jinjun, Yang Dongqing, Jurczyszyn Artur, Beksac Meral, Gu Chunyan, Yang Ye.  (2020)  Dihydroartemisinin Induces Growth Arrest and Overcomes Dexamethasone Resistance in Multiple Myeloma.  Frontiers in Oncology,  10  (767).  [PMID:32500030] [10.3389/fonc.2020.00767]
25. Shuo Zhang, Yan Ma, Juan Feng.  (2020)  Neuroprotective mechanisms of ε-viniferin in a rotenone-induced cell model of Parkinson's disease: significance of SIRT3-mediated FOXO3 deacetylation.  Neural Regeneration Research,  15  (11): ( 2143–2153).  [PMID:32394973] [10.4103/1673-5374.282264]
26. Lu Wang, Liran Zhu, Chenfangyuan Duan, Lu Li, Guangliang Chen.  (2020)  Total saponin of Dioscorea collettii attenuates MSU crystal‑induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase‑1 in THP‑1 macrophages.  Molecular Medicine Reports,  21  (6): (2466-2474).  [PMID:32236574] [10.3892/mmr.2020.11035]
27. Yang Tian, Yongfei Li, Wen-Li Jiang, Dong-Ye Zhou, Junjie Fei, Chun-Yan Li.  (2019)  In-Situ Imaging of Azoreductase Activity in the Acute and Chronic Ulcerative Colitis Mice by a Near-Infrared Fluorescent Probe.  ANALYTICAL CHEMISTRY,  91  (16): (10901–10907).  [PMID:31362489] [10.1021/acs.analchem.9b02857]
28. Siyu Wu, Lili Lei, Yang Song, Mengting Liu, Shibo Lu, Dan Lou, Yonghong Shi, Zhibin Wang, Defu He.  (2018)  Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism.  EXPERIMENTAL NEUROLOGY,  309  (67).  [PMID:30076829] [10.1016/j.expneurol.2018.07.018]
29. Yuzhi Chen, Xiaomin Shi, Zhengliang Lu, Xuefei Wang, Zhuo Wang.  (2017)  A Fluorescent Probe for Hydrogen Peroxide in Vivo Based on the Modulation of Intramolecular Charge Transfer.  ANALYTICAL CHEMISTRY,  89  (10): (5278–5284).  [PMID:28415838] [10.1021/acs.analchem.6b04810]
30. Mei Ping Zhao, Qi Zhi Liu, Qiyong Liu, Zhi Long Liu.  (2017)  Identification of Larvicidal Constituents of the Essential Oil of Echinops grijsii Roots against the Three Species of Mosquitoes.  MOLECULES,  22  (2): (205).  [PMID:28134799] [10.3390/molecules22020205]
31. Guyue Cheng, Bei Li, Chenxi Wang, Hongfei Zhang, Guixia Liang, Zhifei Weng, Haihong Hao, Xu Wang, Zhenli Liu, Menghong Dai, Yulian Wang, Zonghui Yuan.  (2015)  Systematic and Molecular Basis of the Antibacterial Action of Quinoxaline 1,4-Di-N-Oxides against Escherichia coli.  PLoS One,  10  (8): (e0136450).  [PMID:26296207] [10.1371/journal.pone.0136450]
32. Simin Yan, Xu Zhang, Haili Zheng, Danhong Hu, Yongtian Zhang, Qinghua Guan, Lifang Liu, Qilong Ding, Yunman Li.  (2015)  Clematichinenoside inhibits VCAM-1 and ICAM-1 expression in TNF-α-treated endothelial cells via NADPH oxidase-dependent IκB kinase/NF-κB pathway.  FREE RADICAL BIOLOGY AND MEDICINE,  78  (190).  [PMID:25463279] [10.1016/j.freeradbiomed.2014.11.004]
33. Yunjie Xu,Weinan Gao,Yong Zhang,Shanshan Wu,Yanan Liu,Xinyue Deng,Lili Xie,Jiayan Yang,Huimei Yu,Jing Su,Liankun Sun.  (2018-07-18)  ABT737 reverses cisplatin resistance by targeting glucose metabolism of human ovarian cancer cells..  International journal of oncology,  53  ((3)): (1055-1068).  [PMID:30015875]
34. Liu Yang, Yu-Han Sun, Xian-Xian Ji, Yuan-Zhen Wang, Yu-Long Liu, Ying Fu, Fei Ye.  (2024)  A new strategy for efficient detection of triflumuron residues in food: An electrochemical sensor derived from a Cu/Fe-BTC MOF-polymer.  INDUSTRIAL CROPS AND PRODUCTS,  218  (118954).  [10.1016/j.indcrop.2024.118954]
35. Shuwen Zhou, Huijuan Cai, Zhiyong Tang, Siyu Lu.  (2024)  Carbon dots encapsulated zeolitic imidazolate framework-8 as an enhanced multi-antioxidant for efficient cytoprotection to HK-2 cells.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  676  (726).  [PMID:39059279] [10.1016/j.jcis.2024.07.150]
36. Jinxin Yu, Jiayi He, Xuefeng Zhang, Chuxiao Lin, Shiyan Liu, Xin Gong, Xinnian Zeng, Jiali Liu.  (2024)  Differential energy pathways are required for rapid long-term memory formation in the oriental fruit fly, Bactrocera dorsalis.  Journal of Integrative Agriculture,  [10.1016/j.jia.2024.12.015]
37. Xiao-lei ZHANG, Meng-ni HU, Ya-nan LI, Yao WANG, Zhen RONG, Jun MA.  (2025)  Effect of electroacupuncture on MMP-2/9 pathway mediated the blood-brain barrier permeability in mice with Parkinson's disease.  World Journal of Acupuncture-Moxibustion,  [10.1016/j.wjam.2025.01.002]
38. Wei Zhou, Wen Zhang, Wei Geng, Yaoqi Huang, Tong-Kai Zhang, Zi-Qian Yi, Yang Ge, Yao Huang, Ge Tian, Xiao-Yu Yang.  (2024)  External Electrons Directly Stimulate Escherichia coli for Enhancing Biological Hydrogen Production.  ACS Nano,  18  (16): (10840-10849).  [PMID:38616401] [10.1021/acsnano.4c00619]
39. Jia Liu, Zuoyu Chen, Lixue Deng, Chundong Yao, Zhixin Zhou, Cheng Zhou, Yawen Bin, Miaodeng Liu, Liping Wang, Lin Wang, Zheng Wang.  (2025)  Metal-phenolic networks specifically eliminate hypoxic tumors by instigating oxidative and proteotoxic stresses.  Bioactive Materials,  47  (361).  [PMID:40026824] [10.1016/j.bioactmat.2025.01.022]
40. Yi Wang, Nahui Liu, Lifan Hu, Jingsong Yang, Mengmeng Han, Tianjiao Zhou, Lei Xing, Hulin Jiang.  (2024)  Nanoengineered mitochondria enable ocular mitochondrial disease therapy via the replacement of dysfunctional mitochondria.  Acta Pharmaceutica Sinica B,  [PMID:39807326] [10.1016/j.apsb.2024.08.007]
41. Weitong Hu, Shuhan Shi, Yihua Xu, Yunting Zhang, Jingyi Hu, Qiong Bian, Xiaolu Ma, Yuxian Ye, Shengfei Yang, Xiaoxia Sheng, Guang Liang, Tianyuan Zhang, Haibin Wu, Jianqing Gao.  (2024)  Platinum Nanozyme-Loaded Dissolving Microneedles Scavenge ROS and Promote Lineage Progression for Androgenetic Alopecia Treatment.  Small Methods,  (2401176).  [PMID:39422115] [10.1002/smtd.202401176]
42. Li Xinying, Li Weiran, Xie Xinying, Fang Ting, Yang Jingwen, Shen Yue, Wang Yicheng, Wang Hongyan, Tao Liqing, Zhang Heng.  (2025)  ROS Regulate Rotenone-induced SH-SY5Y Dopamine Neuron Death Through Ferroptosis-mediated Autophagy and Apoptosis.  MOLECULAR NEUROBIOLOGY,  (1-19).  [PMID:40097764] [10.1007/s12035-025-04824-6]
43. Fang Shi, Yong-Sheng Gao, Shu-Mei Han, Huan Shi, Qing-Sheng Hou, Yang Gao, Xiao-Wen Wen, Zhen-Yu Zhu, Kai Liu, Wei-Peng Gong, Ben-Shi Wang, Xin Liu, Lei Zou.  (2024)  Targeting MLCK-MLC2 signaling pathway by tagatose alleviates dysregulated mitochondria-associated colonitis.  Journal of Functional Foods,  117  (106222).  [10.1016/j.jff.2024.106222]
44. Jiaxing Huang, Xiaotang Wang, Na Li, Wei Fan, Xingran Li, Qian Zhou, Jiangyi Liu, Wanqian Li, Zhi Zhang, Xiaoyan Liu, Shuhao Zeng, Hui Yang, Meng Tian, Peizeng Yang, Shengping Hou.  (2024)  YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.  Advanced Science,  (2308031).  [PMID:38493498] [10.1002/advs.202308031]

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