| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| O110087-20mg |
20mg |
现货  |
|
| 别名 | 土当归酸 | 石竹素 | 丁香油素 |
|---|---|
| 英文别名 | Caryophyllin | OLEANOLIC_ACID | SMR000445561 | Oleanolic acid, analytical standard | OLEANOLIC ACID (CONSTITUENT OF HOLY BASIL LEAF) [DSC] | (4aS,5S,6aS,6bR,8R,8aR,10S,12aR,12bR,14bS)-10-Hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11 |
| 规格或纯度 | Moligand™, 分析标准品, ≥98% |
| 英文名称 | Oleanolic acid |
| 生化机理 | 天然三萜。各种药理属性。在体外和体内的抗病毒，抗炎，抗血管生成，抗凋亡和抗肿瘤活性。 |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 备注 | 如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 |
| 产品介绍 |
溶于甲醇、乙醇、乙醚、丙酮和氯仿，不溶于水。 齐墩果酸是羟基五环三萜酸（HPTA），具有抗菌、抗肿瘤[和抗利尿作用； Oleanolic acid is a hydroxyl pentacyclic triterpenoic acid (HPTA), which exhibits antibacterial, antitumor and antileishmanial activity. |
| 纯度 | ≥98% |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 208-081-6 |
|---|---|
| 分子类型 | 未知 |
| IIUPAC Name | (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
| INCHI | 1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1 |
| InChi Key | MIJYXULNPSFWEK-GTOFXWBISA-N |
| Smiles | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C |
| Isomeric SMILES | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O |
| 分子量 | 456.7 |
| Beilstein号 | 10(4)1164 |
| Reaxy-Rn | 2228564 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2228564&ln= |
| 密度 | 1.1 |
|---|---|
| 比旋光度 | 76 ° (C=1, CHCl3) |
| 熔点 | 300°C |
| 分子量 | 456.700 g/mol |
| XLogP3 | 7.500 |
| 氢键供体数Hydrogen Bond Donor Count | 2 |
| 氢键受体数Hydrogen Bond Acceptor Count | 3 |
| 可旋转键计数Rotatable Bond Count | 1 |
| 精确质量Exact Mass | 456.36 Da |
| 单同位素质量Monoisotopic Mass | 456.36 Da |
| 拓扑极表面积Topological Polar Surface Area | 57.500 Ų |
| 重原子数Heavy Atom Count | 33 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 885.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 8 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| WGK Germany | 2 |
|---|---|
| RTECS | RK0177965 |
| Merck Index | 6827 |
| 个人防护装备 | dust mask type N95 (US),Eyeshields,Gloves |
| 1. Honglei Bao, Wenyu Sun, Yang Jin, Chaoyue Wang, Xiang Wang, Hengmian Sun, Chu Chu, Shengqiang Tong. (2021) Preparative separation of structural isomeric pentacyclic triterpenes from Eriobotrya japonica (Thunb.) leaves by high speed countercurrent chromatography with hydroxypropyl-β-cyclodextrin as additive. JOURNAL OF CHROMATOGRAPHY A, 1646 (462066). [PMID:33845265] [10.1016/j.chroma.2021.462066] |
| 2. Wang Hanqi, Cheng Fang, He Wei, Zhu Jiaohui, Cheng Gang, Qu Jingping. (2017) Poly(ethylene) glycol hydrogel based on oxa-Michael reaction: Precursor synthesis and hydrogel formation. Biointerphases, 12 (2): [PMID:28571325] [10.1116/1.4984305] |
| 3. Huiling Ma, Yang Liu, Xi Mai, Yijing Liao, Kai Zhang, Bin Liu, Xin Xie, Qiaoli Du. (2016) Identification of the constituents and metabolites in rat plasma after oral administration of HuanglianShangqing pills by ultra high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 125 (194). [PMID:27031575] [10.1016/j.jpba.2016.03.038] |
| 4. Xilin Jiang, Jian Tang, Zhiqiang Gao, Caixia Chen, Wenjun Li, Lu Peng, Hongwei Li, Hongying Zhao, Yun Zhao. (2024) Exploring the protection on islet β-cells and hypoglycemic effect of Moringa oleifera stem based on network pharmacology and experimental validation. Journal of Functional Foods, 122 (106499). [10.1016/j.jff.2024.106499] |
| 5. Shaofei Song, Hong Peng, Yuan Li, Tingting Zhao, Renjie Cao, Lei Zheng, Min Huang, Yiming Jiang. (2024) Oleanolic acid promotes liver regeneration after partial hepatectomy via regulating pregnane X receptor signaling pathway in mice. CHEMICO-BIOLOGICAL INTERACTIONS, 393 (110970). [PMID:38513930] [10.1016/j.cbi.2024.110970] |
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