基本描述

别名	油酸甘油酯 \| 单油酸甘油酯 \| 甘油α-单油酸酯 \| 1-油酰基-rac-甘油 \| rac-甘油 1-单油酸酯 \| 甘油顺-9-十八烯酰基 \| 1-(顺-9- 十八烯酰基)-rac-甘油 \| DL-α-甘油单油酸酯
英文别名	1-Oleylglycerol \| alpha-Monoolein \| Excel O 95F \| Oleoyl glycerol \| 1-Monooleoyl-rac-glycerol \| CHEBI:75342 \| Emery oleic acid ester 2221 \| Nikkol MGO \| rac-1-Monoolein \| Monoolein \| mono-olein \| 1,2,3-Propanetriol mono((Z)-9-octadecenoate) \| 2,3-dihydrox
规格或纯度	Moligand™, ≥50%(HPLC)
英文名称	Monoolein
生化机理	1-油酰基-rac-甘油对脂蛋白脂肪酶介导的甘油三酸酯水解同时呈现抑制和抗抑制作用。甘油单油酸酯（1-油酰-rac-甘油）被用来研发基于甘油单油酸酯的纳米颗粒液体分散剂，作为潜在的给药载体。
储存温度	避光,充氩
运输条件	常规运输
作用类型	激动剂
作用机制	GPR119 的激动剂
产品介绍	1-油酰基-rac-甘油是一种甘油单酸酯，获取自天然油脂。它包含两个活性醇基。它可溶于氯仿和己烷。它可从己烷中结晶。应用： 1-油酰基-rac-甘油已用于：通过两针法与样品混合，利用结晶技术中获得脂质立方相用作单酸甘油酯（MG）脂肪酶测定的底物制备用于测定MG水解酶体外活性的MG溶液 1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.
纯度	≥50%(HPLC)

关联靶点（人）

GPR119 Tclin 葡萄糖依赖性胰岛素促泌剂受体(Glucose-dependent insulinotropic receptor) (1 活性数据)

点击查看靶蛋白信息： GPR119

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

PTGS2 Tclin Cyclooxygenase-2 (13999 活性数据)

点击查看靶蛋白信息： PTGS2

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

PLA2G2A Tchem Phospholipase A2 group IIA (1079 活性数据)

点击查看靶蛋白信息： PLA2G2A

活性类型	Relation	Activity value	Units	Action Type	期刊	PubMed Id	doi	Assay Aladdin ID

作用机制

作用机制	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	参考文献

名称和识别符

EC号	203-809-9
分子类型	小分子
IIUPAC Name	2,3-dihydroxypropyl (Z)-octadec-9-enoate
INCHI	1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChi Key	RZRNAYUHWVFMIP-KTKRTIGZSA-N
Smiles	CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O
Isomeric SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O
分子量	356.54
Beilstein号	1728976
Reaxy-Rn	1728976
Reaxys-RN link address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728976&ln=

化学和物理性质

密度	0.969
敏感性	对湿度、光线、空气敏感
闪点(℉)	309.2 °F
闪点(℃)	154 °C
熔点	35-37°C
分子量	356.500 g/mol
XLogP3	6.500
氢键供体数Hydrogen Bond Donor Count	2
氢键受体数Hydrogen Bond Acceptor Count	4
可旋转键计数Rotatable Bond Count	19
精确质量Exact Mass	356.293 Da
单同位素质量Monoisotopic Mass	356.293 Da
拓扑极表面积Topological Polar Surface Area	66.800 Å²
重原子数Heavy Atom Count	25
形式电荷Formal Charge	0
复杂度Complexity	315.000
同位素原子数Isotope Atom Count	0
定义的原子立体中心计数Defined Atom Stereocenter Count	0
未定义的原子立体中心计数Undefined Atom Stereocenter Count	1
定义的键立体中心计数Defined Bond Stereocenter Count	1
未定义的键立体中心计数Undefined Bond Stereocenter Count	0
所有立体化学键的总数The total count of all stereochemical bonds	1
共价键合单元计数Covalently-Bonded Unit Count	1

安全和危险性（GHS）

信号词	Warning
危险声明	H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 H412: 对水生生物有害并具有长期持续影响 H302: 吞食有害
预防措施声明	P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P273: 避免释放到环境中。
WGK Germany	1
个人防护装备	Faceshields,full-face respirator (US),Gloves,Goggles,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

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找到18个结果

批号(Lot Number)	证书类型	货号
E2512291	分析证书	M107453
E2512355	分析证书	M107453
E2512294	分析证书	M107453
E2512360	分析证书	M107453
F2125069	分析证书	M107453
G2214039	分析证书	M107453
D2430006	分析证书	M107453
F2411070	分析证书	M107453
B2512124	分析证书	M107453
D2430007	分析证书	M107453
I2222007	分析证书	M107453
I2222008	分析证书	M107453
I2222034	分析证书	M107453
I2222035	分析证书	M107453
I2222045	分析证书	M107453
D2425061	分析证书	M107453
C2215287	分析证书	M107453
A2214194	分析证书	M107453

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引用文献

1. Yingzhu Zhang, Jinqi Xu, Cuie Tang, Yan Li. (2023) Crystallization Behavior and Physical Properties of Monoglycerides-Based Oleogels as Function of Oleogelator Concentration. Foods, 12 (2): (345). [PMID:36673437] [10.3390/foods12020345]
2. Qingqing Xu, Xiaoli Qin, Dongming Lan, Xuan Liu, Bo Yang, Sentai Liao, Weifei Wang, Yonghua Wang. (2022) Water-in-oil emulsions enriched with alpha-linolenic acid in diacylglycerol form: Stability, formation mechanism and in vitro digestion analysis. FOOD CHEMISTRY, 391 (133201). [PMID:35609461] [10.1016/j.foodchem.2022.133201]
3. Fu Fangqin, Li Xin, Zheng Tengyi, Xia Xiao, Du Minqun, Huang Zhengwei, Huang Ying, Pan Xin, Wu Chuanbin. (2021) Stability Evaluation of Lyotropic Liquid Crystalline Precursor for the Co-delivery of Chlorhexidine and Silver Nanoparticles. AAPS PHARMSCITECH, 22 (7): (1-9). [PMID:34545436] [10.1208/s12249-021-02102-x]
4. Weiwei Wang, Zhuangzhuang Liu, Qimin Song, Xindi Zhang, Shengkai Jiao, Yao Xu, Quanda Xu, Dezun Sheng. (2021) Tribological performance of organic molybdenum in the presence of organic friction modifier. PLoS One, 16 (6): (e0252203). [PMID:34111128] [10.1371/journal.pone.0252203]
5. Yajing Hu, Zhenxia Du, Xuechun Sun, Xin Ma, Jingdan Song, Haixia Sui, Augustine Atta Debrah. (2021) Non-targeted analysis and risk assessment of non-volatile compounds in polyamide food contact materials. FOOD CHEMISTRY, 345 (128625). [PMID:33601649] [10.1016/j.foodchem.2020.128625]
6. Xiao-Wei Chen, Shang-De Sun, Guo-Long Yang, Chuan-Guo Ma. (2019) Engineering phytosterol-based oleogels for potential application as sustainable petrolatum replacement. RSC Advances, 10 (1): (244-252). [PMID:35492564] [10.1039/C9RA06950J]
7. Shangde Sun, Xuebei Hou. (2019) A novel caffeic acid-based deep eutectic solvent as caffeoyl donor to enhance glycerol caffeates synthesis. JOURNAL OF MOLECULAR LIQUIDS, 277 (556). [10.1016/j.molliq.2018.12.145]
8. Tengyi Zheng, Xintian Huang, Jintian Chen, Disang Feng, Liling Mei, Ying Huang, Guilan Quan, Chune Zhu, Vikramjeet Singh, Hao Ran, Xin Pan, Chuan-Yu Wu, Chuanbin Wu. (2018) A liquid crystalline precursor incorporating chlorhexidine acetate and silver nanoparticles for root canal disinfection. Biomaterials Science, 6 (3): (596-603). [PMID:29406548] [10.1039/C7BM00764G]
9. Han Lidong, Yang Rong, Yuan Shengxiao, Ding Shuang, Wu Ziheng, Wu Zhenghong, Qi Xiaole. (2018) Soft multiple emulsions demonstrating reversible freeze-thawing capacity and enhanced skin permeability of diclofenac sodium. COLLOID AND POLYMER SCIENCE, 296 (3): (471-481). [10.1007/s00396-018-4265-3]
10. Xuan Liu, Chunjin Huang, Dongming Lan, Weifei Wang, Yonghua Wang. (2025) Combining phospholipase A1 with monoacylglycerol lipase for crude vegetable oil degumming through improved oil-water separation. FOOD CHEMISTRY, 467 (142366). [PMID:39644657] [10.1016/j.foodchem.2024.142366]
11. Siliang Ding, Xiaohan Chen, Bo Ouyang, Bo Yang, Weifei Wang, Yonghua Wang. (2024) Exploring Diacylglycerol Oil-Based Oleogels as Effective Stabilizers in Peanut Butter: Performance, Structural Insights, and Sensory Evaluation. Journal of Oleo Science, [PMID:38311404] [10.5650/jos.ess23122]
12. Ruirui Li, Wei Zhuang, Yan Gao, Yahan Bai, Keke Zhang, Zhenfu Wang. (2025) Interfacial modulation of hierarchically porous UIO-66 for the immobilization of Rhizomucor miehei lipase towards the efficient synthesis of 1,3-dioleic acid glycerol. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 291 (138993). [PMID:39710037] [10.1016/j.ijbiomac.2024.138993]
13. Bowen Yang, Tian Zhao, Shengyang Ji, Yan Liu, Minghao Xu, Baiyi Lu. (2024) Molecular dynamics simulations of the interfacial behaviors and photo-oxidation of phytosterol under different emulsion oil content. FOOD CHEMISTRY, 451 (139292). [PMID:38663239] [10.1016/j.foodchem.2024.139292]
14. Huijing Chen, Shanliang Zhong, Guoxiang Chi, Huiying Li, Kewei Chen, Zhirong Wang, Jianquan Kan. (2025) Preparation and functional characteristics of starch-lipid complexes with different oleic acid-rich glycerolipids. FOOD CHEMISTRY, 476 (143450). [PMID:39986078] [10.1016/j.foodchem.2025.143450]

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货号 (SKU)	包装规格	是否现货
M107453-25g	25g	现货
M107453-100g	100g	现货
M107453-500g	500g	现货
M107453-2.5kg	2.5kg	现货
M107453-10kg	10kg	现货

甘油单油酸酯, GPR119 的激动剂

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