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DL-苹果酸

204篇引用文献 COA COA
    级别和纯度:
  • AR
    •
  • ≥99%(T)
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
M101126-100g
 100g 现货 Stock Image
M101126-500g
 500g 现货 Stock Image
M101126-2.5kg
 2.5kg 现货 Stock Image
大包装询价 收藏夹 比较  SDS下载  DATASHEET  质量标准
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代谢物 (8911) 香精香料 (52)
main product photo

基本描述

别名 (±)一羟基丁二酸 | DL-羟基丁二酸 | 羟基丁二酸 | DL-羟基琥珀酸 | (±)-2-羟基琥珀酸
英文别名 DL-Hydroxybutanedioic acid | (±)-2-Hydroxysuccinic acid
规格或纯度 AR, ≥99%(T)
英文名称 DL-Malic acid
储存温度 干燥
运输条件 常规运输
产品介绍

苹果酸在正常情况下稳定，湿度高时有吸湿性。易溶于甲醇、乙醇、丙酮和其他许多极性溶剂。酸性较强，其0.001%水溶液pH值为3.80，0.01%者pH值为2.80，1%者pH值为2.35。离解常数k1为4×10-4，k2为9×10-6。摩尔溶解热-20.516kJ/mol，粘度（SO2水溶液，25℃）6.5mPa·s。用作清凉饮料（如乳酸菌饮料、乳饮料、汽水、可乐）、冷冻食品（如果子露、冰激凌等），加工食品（如果子酒、蛋黄酱）的酸味剂，水果饮料等的色泽保持剂、防腐剂和蛋黄等的乳化稳定剂。用途还包括用作药品、化妆品、洗牙液、金属清洁剂、缓冲剂、纺织工业中的阻凝剂，聚脂纤维的荧光增白剂的原料。


应用：

DL-苹果酸(MA)可用于：

掺杂磷酸二氢铵(ADP)晶体以改善ADP晶体特性。

形成水溶性复合物Nb-MA，进一步与LiCl反应形成铌酸锂(LiNbO3)粉末。

作为单体与DL-乳酸合成聚(DL-乳酸-co-α,β-苹果酸)(PLMA)共聚物，经异硫氰酸荧光素(FITC)修饰后可涂覆磁性Fe3O4纳米颗粒，用作MRI T2型造影剂。
纯度 ≥99%(T)

关联靶点（人）

PKD2L1 Tchem 多囊肾病 2 类蛋白 1(Polycystic kidney disease 2-like 1 protein) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
PTH1R Tclin Parathyroid hormone receptor (47172 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase 1 (404 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EGLN3 Tclin Egl nine homolog 3 (250 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
FTO Tchem Alpha-ketoglutarate-dependent dioxygenase FTO (473 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

ampC Beta-lactamase AmpC (62480 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
Meloidogyne incognita (862 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type 期刊 PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 230-022-8
分子类型 小分子
IIUPAC Name 2-hydroxybutanedioic acid
INCHI 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
InChi Key BJEPYKJPYRNKOW-UHFFFAOYSA-N
Smiles C(C(C(=O)O)O)C(=O)O
Isomeric SMILES C(C(C(=O)O)O)C(=O)O
关联CAS 617-48-1
分子量 134.09
Beilstein号 1723539
Reaxy-Rn 1723539
Reaxys-RN link address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723539&ln=

化学和物理性质

溶解性 Soluble in acetone, ether, water, methanol and ethanol.
密度 1.641
敏感性 对光敏感
闪点(℃) 203 °C
熔点 129-133°C
分子量 134.090 g/mol
XLogP3 -1.300
氢键供体数Hydrogen Bond Donor Count 3
氢键受体数Hydrogen Bond Acceptor Count 5
可旋转键计数Rotatable Bond Count 3
精确质量Exact Mass 134.022 Da
单同位素质量Monoisotopic Mass 134.022 Da
拓扑极表面积Topological Polar Surface Area 94.800 Ų
重原子数Heavy Atom Count 9
形式电荷Formal Charge 0
复杂度Complexity 129.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 0
未定义的原子立体中心计数Undefined Atom Stereocenter Count 1
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

象形图 GHS05,   GHS07
信号词 危险
危险声明

H315: 引起皮肤刺激

H318: 造成严重的眼睛损伤

H319: 引起严重眼睛刺激
预防措施声明

P264: 处理后要彻底洗手。

P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。

P321: 特殊处理（请参阅此标签上的...）。

P302+P352: 如皮肤沾染：用水充分清洗。

P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。

P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。

P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。

P305+P354+P338: 如果进入眼睛：立即用水冲洗几分钟。取下隐形眼镜（如果有的话），并且操作简单。继续冲洗。

P317: 寻求紧急医疗救助。

P337+P317: 如果眼睛刺激持续：寻求医疗帮助。

P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
WGK Germany 3
RTECS ON7175000
Merck Index 5707
个人防护装备 dust mask type N95 (US),Eyeshields,Gloves

质检证书（CoA,COO,BSE/TSE 和分析图谱)

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找到35个结果

批号(Lot Number) 证书类型 货号
J2516607 分析证书 M101126
J2516608 分析证书 M101126
J2516609 分析证书 M101126
I2503781 分析证书 M101126
I2503790 分析证书 M101126
H2113239 分析证书 M101126
E2513364 分析证书 M101126
E2513365 分析证书 M101126
E2513366 分析证书 M101126
K2411455 分析证书 M101126
K2411453 分析证书 M101126
K2411454 分析证书 M101126
D2521105 分析证书 M101126
G2417136 分析证书 M101126
G2417138 分析证书 M101126
G2417148 分析证书 M101126
D2416362 分析证书 M101126
D2416364 分析证书 M101126
D2416366 分析证书 M101126
K2321505 分析证书 M101126
K2321506 分析证书 M101126
K2321511 分析证书 M101126
I2305584 分析证书 M101126
I2305585 分析证书 M101126
I2305586 分析证书 M101126
C2317885 分析证书 M101126
C2317892 分析证书 M101126
C2317926 分析证书 M101126
J2317053 分析证书 M101126
H2212307 分析证书 M101126
H2212317 分析证书 M101126
H2212370 分析证书 M101126
B2216384 分析证书 M101126
B2216418 分析证书 M101126
B2216419 分析证书 M101126

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