| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| C110080-20mg |
20mg |
现货  |
| |
| C110080-100mg |
100mg |
现货 |
|
| 别名 | 3'-脱氧腺苷 |
|---|---|
| 英文别名 | Cordycepin, from Cordyceps militaris | CORDYCEPIN [MI] | 9-(3-Deoxy-b-D-erythro-pentofuranosyl)-9H-purin-6-amine | Cordycepin, >=98.0% (HPLC) | UNII-GZ8VF4M2J8 | AC-22613 | MFCD00037998 | NSC-63984 | Q2256677 | Z3041517973 | AKOS015854875 | (2R,3R,5S)-2-( |
| 规格或纯度 | Moligand™, 分析标准品, ≥99%(HPLC) |
| 英文名称 | Cordycepin |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
虫草是一种腺苷类似物，很容易转化为虫草5'-三磷酸;可作为RNA3' -末端标记使用 |
| 纯度 | ≥99%(HPLC) |
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
| EC号 | 200-791-4 |
|---|---|
| 分子类型 | 小分子 |
| IIUPAC Name | (2R,3R,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol |
| INCHI | 1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1 |
| InChi Key | OFEZSBMBBKLLBJ-BAJZRUMYSA-N |
| Smiles | C1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO |
| Isomeric SMILES | C1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)CO |
| UN Number | 2811 |
| 分子量 | 251.24 |
| Beilstein号 | 35194 |
| Reaxy-Rn | 7169449 |
| Reaxys-RN link address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7169449&ln= |
| 密度 | 1.91 |
|---|---|
| 比旋光度 | -46° (C=1,H2O) |
| 熔点 | 224-228°C |
| 分子量 | 251.240 g/mol |
| XLogP3 | -1.200 |
| 氢键供体数Hydrogen Bond Donor Count | 3 |
| 氢键受体数Hydrogen Bond Acceptor Count | 7 |
| 可旋转键计数Rotatable Bond Count | 2 |
| 精确质量Exact Mass | 251.102 Da |
| 单同位素质量Monoisotopic Mass | 251.102 Da |
| 拓扑极表面积Topological Polar Surface Area | 119.000 Ų |
| 重原子数Heavy Atom Count | 18 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 307.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 3 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 象形图 | GHS06, GHS07 |
|---|---|
| 信号词 | 危险 |
| 危险声明 |
H301: 吞咽会中毒 H315: 引起皮肤刺激 H319: 引起严重眼睛刺激 H335: 可能引起呼吸道刺激 |
| 预防措施声明 |
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾 P264: 处理后要彻底洗手。 P270: 使用本产品时，请勿进食、饮水或吸烟。 P271: 仅在室外或通风良好的地方使用。 P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。 P321: 特殊处理（请参阅此标签上的...）。 P330: 漱口 P302+P352: 如皮肤沾染：用水充分清洗。 P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。 P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364: 脱掉沾污的衣服，清洗后方可重新使用。 P405: 密闭存放 P403+P233: 存放在通风良好的地方。保持容器密闭。 P501: 将内容物/容器处理到。。。 P264+P265: 处理后彻底洗手[和…]。不要触摸眼睛。 P301+P316: 如果吞咽：立即寻求紧急医疗救助。 P337+P317: 如果眼睛刺激持续：寻求医疗帮助。 P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。 P319: 如果你感到不适，请寻求医疗帮助。 |
| WGK Germany | 3 |
| RTECS | AU7358610 |
| Class | 6.1 |
| Merck Index | 2529 |
| 个人防护装备 | Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges |
| 1. Baiyi Yan, Yanchun Gong, Wei Meng, Huizhen Sun, Wenxi Li, Kaizhi Ding, Caixia Dang, Xiaofei Gao, Wei Sun, Chunhua Yuan, Songhua Wang, Li-Hua Yao. (2023) Cordycepin protects islet β-cells against glucotoxicity and lipotoxicity via modulating related proteins of ROS/JNK signaling pathway. BIOMEDICINE & PHARMACOTHERAPY, 163 (114776). [PMID:37100012] [10.1016/j.biopha.2023.114776] |
| 2. Xinyue Li, Yuanyuan Fan, Zhengbao Zha, Deyan Gong, Jiajia Yu, Qianhui Li, Ruoyao Li, Hua Wang, Fei Wang. (2023) Cordycepin-Loaded Macrophage Vesicles for Targeted Nonalcoholic Steatohepatitis Attenuation. ADVANCED FUNCTIONAL MATERIALS, 33 (18): (2214059). [10.1002/adfm.202214059] |
| 3. Ya Chen, Yuan Jiang, Xinyu Huang, Lin Chen, Hao Yang, Jian Zhao, Beibei Liang. (2022) Cordycepin Inhibits the Growth of Hepatocellular Carcinoma by Regulating the Pathway of Aerobic Glycolysis. Evidence-based Complementary and Alternative Medicine, 2022 (6454482). [PMID:36467556] [10.1155/2022/6454482] |
| 4. Yu Wang, Zejun Pei, Zaixiang Lou, Hongxin Wang. (2022) Evaluation of Anti-Biofilm Capability of Cordycepin Against Candida albicans. Infection and Drug Resistance, [PMID:33574683] [10.2147/IDR.S285690] |
| 5. Weng Chunyue, Mi Zheyan, Li Meijing, Qin Haibin, Hu Zhongce, Liu Zhiqiang, Zheng Yuguo, Wang Yuanshan. (2022) Improvement of S-adenosyl-L-methionine production in Saccharomyces cerevisiae by atmospheric and room temperature plasma-ultraviolet compound mutagenesis and droplet microfluidic adaptive evolution. 3 Biotech, 12 (9): (1-15). [PMID:35975026] [10.1007/s13205-022-03297-x] |
| 6. Huizhen Sun, Anyong Zhang, Yanchun Gong, Wei Sun, Baiyi Yan, Shuihong Lei, Li-Hua Yao. (2022) Improving effect of cordycepin on insulin synthesis and secretion in normal and oxidative-damaged INS-1 cells. EUROPEAN JOURNAL OF PHARMACOLOGY, 920 (174843). [PMID:35196519] [10.1016/j.ejphar.2022.174843] |
| 7. Jing Yang, Yiwen Zhou, Jinsong Shi. (2020) Cordycepin protects against acute pancreatitis by modulating NF-κB and NLRP3 inflammasome activation via AMPK. LIFE SCIENCES, 251 (117645). [PMID:32268154] [10.1016/j.lfs.2020.117645] |
| 8. Hao Song, Li-Ping Huang, Yuping Li, Chao Liu, Songhua Wang, Wei Meng, Shanshan Wei, Xin-Ping Liu, Yanchun Gong, Li-Hua Yao. (2018) Neuroprotective effects of cordycepin inhibit Aβ-induced apoptosis in hippocampal neurons. NEUROTOXICOLOGY, 68 (73). [PMID:30031108] [10.1016/j.neuro.2018.07.008] |
| 9. Qi Yize, Zhou Yao, Li Jiyang, Zhu Fangyuan, Guo Gengni, Wang Can, Yu Man, Wang Yijie, Ma Tengfei, Feng Shanwu, Zhou Li. (2024) 3′-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome. Neural Regeneration Research, 19 (10): (2270). [PMID:38488561] [10.4103/1673-5374.392887] |
| 10. Yanhong Bi, Ruiping Fu, Weiliang Hua, Xinyu Xiong, Chun Zhu, Xiaobao Nie, Zhaoyu Wang. (2025) An empirical exploration of the capacity of choline chloride/lactic acid eutectics to extract and stabilize natural polyhydroxy compounds. FOOD CHEMISTRY, (143873). [PMID:40120314] [10.1016/j.foodchem.2025.143873] |
| 11. Zhu Liang, Keyan Zhang, Hongli Guo, Xujiao Tang, Mingzhu Chen, Jinsong Shi, Jing Yang. (2024) Cordycepin alleviates hepatic fibrosis in association with the inhibition of glutaminolysis to promote hepatic stellate cell senescence. INTERNATIONAL IMMUNOPHARMACOLOGY, 132 (111981). [PMID:38565039] [10.1016/j.intimp.2024.111981] |
| 12. Chen Ya, Zhu Congcong, Tai Zongguang, Lian Tianyan, Zhu Quangang, Chen Zhongjian. (2024) Cordycepin Ameliorates Psoriasis-Like Skin Lesion by Regulating p53/MDM2 Feedback Loop. MOLECULAR BIOTECHNOLOGY, (1-12). [PMID:38914920] [10.1007/s12033-024-01211-9] |
| 13. Huizhen Sun, Shanshan Wei, Yanchun Gong, Kaizhi Ding, Shan Tang, Wei Sun, Chunhua Yuan, Liping Huang, Zhibing Liu, Chong Chen, Lihua Yao. (2024) Neuroprotective effects of cordycepin inhibit glutamate-induced apoptosis in hippocampal neurons. CELL STRESS & CHAPERONES, [PMID:38219840] [10.1016/j.cstres.2024.01.001] |
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