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疾病研究

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  1. Recombinant Human CD47 Protein
      种属: 人(Human)    Accession #: Q08722    
      表达系统: HEK293    蛋白标签: C-hFc    内毒素水平: <1.0 EU/μg    
      生物活性: 1. Measured by its binding ability in a functional ELISA. Immobilized human B7-H7/HHLA2 Protein at 10 μg/mL can bind Recombinant Human CD47 Protein (rp144028), the EC50 of human CD47 Protein is 50.0 - 200.0 ng/mL. 2. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CD47 Protein (rp144028) at 1 μg/mL can bind Magrolimab (anti-CD47) (Ab169323) with the EC50 of 10.34 ng/mL.    
  2. Recombinant Mouse CD47 Protein
      种属: 小鼠(Mouse)    Accession #: NP_034711    
      表达系统: HEK293    蛋白标签: C-His    内毒素水平: <0.1 EU/μg    
      生物活性: Measured by its binding ability in a functional ELISA. When Recombinant Mouse SIRP alpha /CD172a Fc Chimera is coated at 2 μg/mL, Recombinant Mouse CD47 binds with an apparent Kd <0.6 nM. Also measured by its ability to antagonize mouse red blood cell adhesion to immobilized Recombinant Mouse SIRP alpha /CD172a Fc Chimera. The ED50 for this effect is 2.0-8.0 μg/mL. Optimal dilutions should be determined by each laboratory for each application.    
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